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Anti-LAMP1 Antibody (3R897)

😃Good
Catalog No. TMAB-01045

Anti-LAMP1 Antibody (3R897) is a Mouse antibody targeting LAMP1. Anti-LAMP1 Antibody (3R897) can be used in WB,ELISA.

Anti-LAMP1 Antibody (3R897)

Anti-LAMP1 Antibody (3R897)

😃Good
Catalog No. TMAB-01045
Anti-LAMP1 Antibody (3R897) is a Mouse antibody targeting LAMP1. Anti-LAMP1 Antibody (3R897) can be used in WB,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$297 7-10 days
100 μL$489 7-10 days
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Product Introduction

Bioactivity
Description
Anti-LAMP1 Antibody (3R897) is a Mouse antibody targeting LAMP1. Anti-LAMP1 Antibody (3R897) can be used in WB,ELISA.
Ig Type
IgG1,k
Clone
3R897
Reactivity
Human (predicted:African Green Monkey)
Verified Activity
Sample:
Lane 1: Human HT1080 cell lysates
Lane 2: Human Hela cell lysates
Lane 3: Human U937 cell lysates
Primary: Anti-LAMP1 (TMAB-01045) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 42 kDa
Observed band size: 90-120 kDa
Application
WB,ELISA
Recommended Dose
WB: 1:500-1000; ELISA: 1:5000-10000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundLysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human LAMP1
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Signal Transduction,Autophagy,Autophagy and mitophagy,SARS Coronavirus,Growth Cone,Soma marker,Neurogenesis,lamp1,Organelle Proteins,B Lymphocytic Lineage,T Lymphocytic Lineage,Monocytic Lineage,Lysosome
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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