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Anti-LAMP1 Antibody (3R897)
😃Good
Catalog No. TMAB-01045
Alias lysosomal-associated membrane protein 1
Anti-LAMP1 Antibody (3R897) is a Mouse antibody targeting LAMP1. Anti-LAMP1 Antibody (3R897) can be used in WB,ELISA.
Anti-LAMP1 Antibody (3R897)
Anti-LAMP1 Antibody (3R897)
😃Good
Catalog No. TMAB-01045Alias lysosomal-associated membrane protein 1
Anti-LAMP1 Antibody (3R897) is a Mouse antibody targeting LAMP1. Anti-LAMP1 Antibody (3R897) can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $489 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-LAMP1 Antibody (3R897) is a Mouse antibody targeting LAMP1. Anti-LAMP1 Antibody (3R897) can be used in WB,ELISA. |
| Alias | lysosomal-associated membrane protein 1 |
| Ig Type | IgG1,k |
| Clone | 3R897 |
| Reactivity | Human (predicted:African Green Monkey) |
| Verified Activity | Sample: Lane 1: Human HT1080 cell lysates Lane 2: Human Hela cell lysates Lane 3: Human U937 cell lysates Primary: Anti-LAMP1 (TMAB-01045) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 42 kDa Observed band size: 90-120 kDa |
| Application | WB,ELISA |
| Recommended Dose | WB: 1:500-1000; ELISA: 1:5000-10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation. |
| Immunogen | KLH conjugated synthetic peptide: human LAMP1 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal Transduction,Autophagy,Autophagy and mitophagy,SARS Coronavirus,Growth Cone,Soma marker,Neurogenesis,lamp1,Organelle Proteins,B Lymphocytic Lineage,T Lymphocytic Lineage,Monocytic Lineage,Lysosome |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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