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Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFKBIA (Tyr305). Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFKBIA (Tyr305). Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat,Monkey |
Application | |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Appearance | Liquid |
Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | Peptide sequence around phosphorylation site of Tyrosine 305(L-P-Y(p)-D-D) derived from Human I kappaB- alpha |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 39 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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