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Anti-A1AR Polyclonal Antibody
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Catalog No. TMAB-00015
Alias ADORA1, Adenosine receptor A1
Anti-A1AR Polyclonal Antibody is a Rabbit antibody targeting A1AR. Anti-A1AR Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-A1AR Polyclonal Antibody
Anti-A1AR Polyclonal Antibody
😃Good
Catalog No. TMAB-00015Alias ADORA1, Adenosine receptor A1
Anti-A1AR Polyclonal Antibody is a Rabbit antibody targeting A1AR. Anti-A1AR Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-A1AR Polyclonal Antibody is a Rabbit antibody targeting A1AR. Anti-A1AR Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | ADORA1, Adenosine receptor A1 |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Horse,Rabbit) |
| Verified Activity | Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-ADORA1 Polyclonal Antibody, Unconjugated (TMAB-00015) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway. |
| Immunogen | KLH conjugated synthetic peptide: human ADORA1 |
| Antigen Species | Human |
| Gene Name | ADORA1 |
| Gene ID | |
| Protein Name | Adenosine receptor A1 |
| Uniprot ID | |
| Biology Area | Associated Proteins,Ischemia / Reperfusion,Inflammatory mediators,Cardiac arrhythmias,Associated Proteins,Macrophage / Inflamm.,Neurogenesis,GPCR |
| Function | Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
| Molecular Weight | Theoretical: 37 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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