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Anti-A1AR Polyclonal Antibody (Synonyms: ADORA1, Adenosine receptor A1)

Catalog No. TMAB-00015 Copy Product Info
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Anti-A1AR Polyclonal Antibody is a Rabbit antibody targeting A1AR. Anti-A1AR Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.

Anti-A1AR Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-00015
Synonyms ADORA1, Adenosine receptor A1

Anti-A1AR Polyclonal Antibody is a Rabbit antibody targeting A1AR. Anti-A1AR Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.

Anti-A1AR Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-A1AR Polyclonal Antibody is a Rabbit antibody targeting A1AR. Anti-A1AR Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
SynonymsADORA1, Adenosine receptor A1
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Horse,Rabbit)
Verified Activity
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-ADORA1 Polyclonal Antibody, Unconjugated (TMAB-00015) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
verifiedActivity
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundAdenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ADORA1
Antigen Species
Human
Gene Name
ADORA1
Gene ID
Protein Name
Adenosine receptor A1
Uniprot ID
Biology Area
Associated Proteins,Ischemia / Reperfusion,Inflammatory mediators,Cardiac arrhythmias,Associated Proteins,Macrophage / Inflamm.,Neurogenesis,GPCR
Function
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Chemical Properties
Molecular WeightTheoretical: 37 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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