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Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody
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Catalog No. TMAC-03107
Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PDCD4 (Ser457). Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody can be used in WB.
Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody
Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody
😃Good
Catalog No. TMAC-03107
Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PDCD4 (Ser457). Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PDCD4 (Ser457). Anti-Phospho-PDCD4 (Ser457) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 457 (F-V-S(p)-E-G) derived from Human PDCD4 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 51 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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