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Asperphenamate

Name: Asperphenamate
Brand: TargetMol
SKU: T10390
Price: 112 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10390Cas No. 63631-36-7

Asperphenamate is a fungal metabolite of Aspergillus flatiipes. The IC50s for T47D cells, MDA-MB-231 cells, and HL-60 cells are 92.3 μM, 96.5 μM, and 97.9 μM. Asperphenamate shows an anticancer effect.

Asperphenamate

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Purity: 99.76%

Catalog No. T10390Cas No. 63631-36-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$112	In Stock	In Stock
5 mg	$286	In Stock	In Stock
10 mg	$397	In Stock	In Stock
25 mg	$592	In Stock	In Stock
50 mg	$822	In Stock	In Stock
100 mg	$1,110	In Stock	In Stock
500 mg	$2,230	-	In Stock
1 mL x 10 mM (in DMSO)	$316	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.76%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Asperphenamate is a fungal metabolite of Aspergillus flatiipes. The IC50s for T47D cells, MDA-MB-231 cells, and HL-60 cells are 92.3 μM, 96.5 μM, and 97.9 μM. Asperphenamate shows an anticancer effect.
In vitro	Asperphenamate induces autophagy and inhibits cancer cell proliferation. Asperphenamate inhibits cathepsin L and also weakly inhibits cathepsin S[1].

Chemical Properties

Molecular Weight	506.59
Formula	C₃₂H₃₀N₂O₄
Cas No.	63631-36-7
Smiles	O=C(OC[C@H](Cc1ccccc1)NC(=O)c1ccccc1)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
Relative Density.	1.198g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (177.66 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (6.51 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9740 mL	9.8699 mL	19.7398 mL	98.6991 mL
5 mM	0.3948 mL	1.9740 mL	3.9480 mL	19.7398 mL
10 mM	0.1974 mL	0.9870 mL	1.9740 mL	9.8699 mL
20 mM	0.0987 mL	0.4935 mL	0.9870 mL	4.9350 mL
50 mM	0.0395 mL	0.1974 mL	0.3948 mL	1.9740 mL
100 mM	0.0197 mL	0.0987 mL	0.1974 mL	0.9870 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc