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Anti-PHYH Antibody (3G140)
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Catalog No. TMAY-02575
Alias RD, phytanoyl-CoA 2-hydroxylase, PHYH1, PAHX, LNAP1, LN1
Anti-PHYH Antibody (3G140) is a Mouse antibody targeting PHYH. Anti-PHYH Antibody (3G140) can be used in IHC-P.
Anti-PHYH Antibody (3G140)
Anti-PHYH Antibody (3G140)
😃Good
Catalog No. TMAY-02575Alias RD, phytanoyl-CoA 2-hydroxylase, PHYH1, PAHX, LNAP1, LN1
Anti-PHYH Antibody (3G140) is a Mouse antibody targeting PHYH. Anti-PHYH Antibody (3G140) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: IHC-P Reactivity: Human |
| Alias | RD, phytanoyl-CoA 2-hydroxylase, PHYH1, PAHX, LNAP1, LN1 |
| Ig Type | Mouse IgG1 |
| Clone | 3G140 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human PHYH in human kidney with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PHYH (rh PHYH; TMPY-03109; O14832; Ser31-Leu338). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentosa, peripheral neuropathy, cerebellar ataxia, and elevated protein levels in the cerebrospinal fluid (CSF). Patients exhibit accumulation of the branched-chain fatty acid, phytanic acid, in blood and tissues. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PHYH Protein (TMPY-03109) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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