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Disopyramide

🥰Excellent
Catalog No. T1320Cas No. 3737-09-5
Alias Triombrin, Hypaque sodium, amidotrizoate sodium

Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.

Disopyramide
Other Forms of Disopyramide:

Disopyramide

🥰Excellent
Purity: 99.62%
Catalog No. T1320Alias Triombrin, Hypaque sodium, amidotrizoate sodiumCas No. 3737-09-5
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$40In StockIn Stock
50 mg$56In StockIn Stock
100 mg$79In StockIn Stock
200 mg$116In Stock-
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.62%
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COA HNMR HPLC LCMS

Product Introduction

Bioactivity
Description
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
SynonymsTriombrin, Hypaque sodium, amidotrizoate sodium
Chemical Properties
Molecular Weight339.47
FormulaC21H29N3O
Cas No.3737-09-5
SmilesCC(C)N(CCC(C(N)=O)(c1ccccc1)c1ccccn1)C(C)C
Relative Density.1.0779 g/cm3 (Estimated)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (147.29 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (14.73 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9458 mL14.7288 mL29.4577 mL147.2884 mL
5 mM0.5892 mL2.9458 mL5.8915 mL29.4577 mL
10 mM0.2946 mL1.4729 mL2.9458 mL14.7288 mL
20 mM0.1473 mL0.7364 mL1.4729 mL7.3644 mL
50 mM0.0589 mL0.2946 mL0.5892 mL2.9458 mL
100 mM0.0295 mL0.1473 mL0.2946 mL1.4729 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ventricularSodiumChannelSodium ChannelSC-7031SC7031SC 7031PotassiumChannelPotassium ChannelnegativeNa+ channelsNa channelsmAChRKcsAinotropicInhibitorinhibitDisopyramideDicorantilatrialarrhythmiasantiarrhythmicaction
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