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Perflubron

🥰Excellent
Catalog No. T16471Cas No. 423-55-2
Alias PFOB, Perfluorooctyl bromide

Perflubron (Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography.

Perflubron

Perflubron

🥰Excellent
Catalog No. T16471Alias PFOB, Perfluorooctyl bromideCas No. 423-55-2
Perflubron (Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography.
Pack SizePriceAvailabilityQuantity
100 mg$29 In Stock
500 mg$64 In Stock
1 g$94 In Stock
1 mL x 10 mM (in DMSO)$29 In Stock
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Purity:≥98%
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Product Introduction

Bioactivity
Description
Perflubron (Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography.
Animal Research
I. Magnetic Resonance Imaging (MRI) Application
1. Material Preparation:
1) Perflubron Emulsion: Perflubron is mixed with phosphatidylcholine (EYP) to form a stable emulsion. The concentration of Perflubron in the emulsion is usually 10%-40%.
2) Phosphatidylcholine (EYP): A lipid used to emulsify Perflubron, enhancing its solubility and stability in the aqueous phase.
3) MRI Equipment: Magnetic resonance imaging equipment equipped with high-resolution imaging capabilities.
2. Steps:
1) Preparation: Perflubron is mixed with EYP in a sterile environment to form a stable emulsion, and the concentration is adjusted according to imaging needs.
2) Injection: The emulsion is administered to the patient by intravenous injection, and an MRI scan is performed after the injection.
3) MRI Imaging: An MRI scan is performed and the distribution of the contrast agent is monitored. Perflubron can enhance tissue contrast, especially when monitoring vascular flow or assessing blood volume.
4) After imaging: Perflubron is usually excreted quickly through the lungs, which helps reduce the patient's exposure to contrast agents.
2. Ultrasound examination application
1. Material preparation:
1) Perflubron emulsion: As with magnetic resonance imaging, Perflubron emulsion is emulsified with lecithin to form a microbubble solution suitable for ultrasound imaging.
2) Ultrasound equipment: High-frequency ultrasound equipment that can detect microbubble signals.
2. Steps:
1) Preparation and injection: Prepare Perflubron microbubble emulsion and perform ultrasound examination after intravenous injection.
2) Imaging: Use ultrasound equipment to image blood vessels and tissue structures. Perflubron microbubbles can significantly improve the clarity of blood vessels and tissue boundaries.
3) After imaging: Microbubbles are usually excreted through the lungs, providing a fast, non-invasive imaging method.
Precautions:
1) Dosage: The dose should be reasonably selected according to the imaging procedure and the specific situation of the patient to avoid excessive doses that lead to unnecessary exposure.
2) Patient safety: As with all contrast agents, there is a risk of allergic reactions. Patients should be monitored during and after the injection to detect adverse reactions.
3) Excretion monitoring: Although Perflubron is excreted rapidly, its excretion through the lungs must be monitored to avoid respiratory problems.
AliasPFOB, Perfluorooctyl bromide
Chemical Properties
Molecular Weight498.96
FormulaC8BrF17
Cas No.423-55-2
SmilesFC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
Relative Density.1.93 g/cm3 at 25℃ (lit.)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (100.21 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0042 mL10.0208 mL20.0417 mL100.2084 mL
5 mM0.4008 mL2.0042 mL4.0083 mL20.0417 mL
10 mM0.2004 mL1.0021 mL2.0042 mL10.0208 mL
20 mM0.1002 mL0.5010 mL1.0021 mL5.0104 mL
50 mM0.0401 mL0.2004 mL0.4008 mL2.0042 mL
100 mM0.0200 mL0.1002 mL0.2004 mL1.0021 mL

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