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Poly-L-lysine hydrochloride

Catalog No. T40240 CAS 26124-78-7

Poly-L-lysine hydrochloride plays a key role in promoting cell attachment to solid substrates by enhancing the electrostatic interaction between the negatively charged ions present on the cell membrane and the surface of the culture substrate as a non-specific attachment factor.Poly-L-lysine hydrochloride is a peptide that at low concentrations Due to its cationic peptide nature, Poly-L-lysine hydrochloride is antimicrobially active. These properties make it an important component for enhancing cell adhesion, regulating phase separation kinetics and demonstrating antimicrobial activity.

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Poly-L-lysine hydrochloride Chemical Structure

Poly-L-lysine hydrochloride, CAS 26124-78-7

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

In vitro

Poly-L-lysine, a food-grade antimicrobial peptide, interacts with proteins to form complexes, serving as potential carriers for the targeted delivery of agents. The interaction affinity was analyzed using electrostatic potential modeling of Poly-L-lysine, resulting in a three-dimensional phase boundary curve that delineates the complexation process into nano-scale formations and phase separation.

Molecular Weight	182.65
CAS No.	26124-78-7

Storage

store at low temperature,keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 45.0 mg/mL, Sonication and heating are recommended.

References and Literature

1. Archishman Ghosh, et al. Three archetypical classes of macromolecular regulators of protein liquid-liquid phase separation. Proc Natl Acad Sci U S A. 2019;116(39):19474-19483. 2. Liang Guo, et al. pH-induced structural transition during complexation and precipitation of sodium caseinate and ε-Poly-l-lysine. Int J Biol Macromol. 2020;154:644-653. 3. Li Z, et al. Sustained delivery and expression of plasmid DNA based on biodegradable polyester, poly(D,L-lactide-co-4-hydroxy-L-proline). J Control Release. 2004;98(3):437-446.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Poly-L-lysine hydrochloride 26124-78-7 Microbiology/Virology Antibacterial Poly-L-lysine Hydrochloride Poly L lysine hydrochloride PolyLlysine hydrochloride inhibitor inhibit

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