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FeTPPS, a decomposition catalyst for 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin iron(III) chloride peroxynitrite, exhibits marked neuroprotective effects in experimental spinal cord injury models. It reduces cerebral tissue inflammation and damage, inhibits nitric oxide production and apoptosis, and may be employed in traumatic brain injury (TBI) research.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $31 | In Stock | |
10 mg | $50 | In Stock | |
25 mg | $94 | In Stock | |
50 mg | $155 | In Stock | |
100 mg | $228 | In Stock |
Description | FeTPPS, a decomposition catalyst for 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin iron(III) chloride peroxynitrite, exhibits marked neuroprotective effects in experimental spinal cord injury models. It reduces cerebral tissue inflammation and damage, inhibits nitric oxide production and apoptosis, and may be employed in traumatic brain injury (TBI) research. |
In vitro | Methods: HepG2 human hepatocellular carcinoma cells were treated with FeTPPS (5, 10, 15, 20, 25 μM for 12 hours), and cell viability was assessed via MTT assay. Results: FeTPPS protected cells from H₂O₂-induced oxidative damage.[2] |
Molecular Weight | 1024.27 |
Formula | C44H28ClFeN4O12S4 |
Cas No. | 90384-82-0 |
Smiles | O=S([O-])(C1=CC=C(C(C(C=C2)=[N]3C2=C(C4=CC=C5C(C6=CC=C(S(=O)([O-])=O)C=C6)=C7C=C8)C9=CC=C(S(=O)([O-])=O)C=C9)=C%10C=CC%11=C(C%12=CC=C(S(=O)([O-])=O)C=C%12)C8=[N]7[Fe+3]3([Cl-])([N-]45)[N-]%10%11)C=C1)=O.[H+].[H+].[H+].[H+] |
Color | Brown |
Appearance | Solid |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
Solubility Information | H2O: 4 mg/mL (3.91 mM), Sonication and heating are recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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