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CD47 Protein, Rhesus macaque, Recombinant (hFc)

(Synonyms: Protein MER6, MER6, Leukocyte Surface Antigen CD47, Integrin-Associated Protein, IAP, CD47, Antigenic Surface Determinant Protein OA3) Copy Product Info

Synonyms: Protein MER6, MER6, Leukocyte Surface Antigen CD47, Integrin-Associated Protein, IAP, CD47, Antigenic Surface Determinant Protein OA3

Catalog No. TMPJ-00613 Copy Product Info
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7A802.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7A802.
Species
Rhesus
Expression System
HEK293 Cells
TagC-hFc
Accession NumberF7A802
Amino AcidGln19-Pro139
ConstructionGln19-Pro139
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsProtein MER6, MER6, Leukocyte Surface Antigen CD47, Integrin-Associated Protein, IAP, CD47, Antigenic Surface Determinant Protein OA3
Research Background
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
Chemical Properties
Molecular Weight60-90 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: CD47 Protein, Rhesus macaque, Recombinant (hFc) chemical structure | CD47 Protein, Rhesus macaque, Recombinant (hFc) molecular weight