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Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $80 | 7-10 days | |
| 10 μg | $129 | 7-10 days | |
| 20 μg | $198 | 7-10 days | |
| 50 μg | $390 | 7-10 days | |
| 100 μg | $626 | 7-10 days | |
| 200 μg | $987 | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | |
| 1 mg | $2,730 | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | P53816 |
| Synonyms | Renal Carcinoma Antigen NY-REN-65,PLA2G16,HRSL3,HREV107-3,HREV107-1,HREV107,H-Rev 107 Protein Homolog,HRASLS3,HRAS-Like Suppressor 3,HRAS-Like Suppressor 1,Group XVI Phospholipase A1/A2,AdPLA,Adipose-Specific Phospholipase A2 |
| Amino Acid | Asp12-Asp132 |
| Construction | Asp12-Asp132 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Molecular Weight | 15 KDa (reducing condition) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, pH8.0. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models. |

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