Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 129.00 | |
50 μg | 5 days | $ 390.00 | |
500 μg | 5 days | $ 1,900.00 | |
1 mg | 5 days | $ 2,730.00 |
Description | Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models. |
Species | Human |
Expression System | E. coli |
Tag | N-6His |
Accession Number | P53816 |
Synonyms | Renal Carcinoma Antigen NY-REN-65, HRAS-Like Suppressor 1, HRSL3, HREV107, AdPLA, HREV107-3, HRASLS3, HRAS-Like Suppressor 3, Group XVI Phospholipase A1/A2, Adipose-Specific Phospholipase A2, HREV107-1, H-Rev 107 Protein Homolog, PLA2G16 |
Amino Acid | Asp12-Asp132 |
Construction | Recombinant Human Phospholipase A2 Group XVI is produced by our E.coli expression system and the target gene encoding Asp12-Asp132 is expressed with a 6His tag at the N-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 15 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM EDTA, pH8.0. |
Stability & Storage |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Shipping |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models. |
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PLA2G16 Protein, Human, Recombinant (His) HRASLS 3 Renal Carcinoma Antigen NY-REN-65 HRAS-Like Suppressor 1 HRSL3 HREV-107 HREV107 AdPLA HREV107-3 HREV 107 HRASLS3 HRAS-Like Suppressor 3 HRSL-3 HRASLS-3 Group XVI Phospholipase A1/A2 Adipose-Specific Phospholipase A2 HREV107-1 HRSL 3 H-Rev 107 Protein Homolog PLA2G16 recombinant recombinant-proteins proteins protein