Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM). It is selective for EGFR over an assortment of other tyrosine and serine/threonine kinases. Cellular studies indicate that BPIQ-II can enter cells and very selectively shut down EGF-stimulated signal transmission by binding competitively at the ATP site of EGFR.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 228.00 | |
5 mg | 35 days | $ 1,590.00 |
Description | BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM). It is selective for EGFR over an assortment of other tyrosine and serine/threonine kinases. Cellular studies indicate that BPIQ-II can enter cells and very selectively shut down EGF-stimulated signal transmission by binding competitively at the ATP site of EGFR. |
Molecular Weight | 376.64 |
Formula | C15H11BrClN5 |
CAS No. | 171179-37-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL
DMSO:PBS (pH 7.2)(1:9): 0.1 mg/mL
DMF: 10 mg/mL
You can also refer to dose conversion for different animals. More
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BPIQ-II (hydrochloride) 171179-37-6 BPIQ-II BPIQII (hydrochloride) BPIQ II (hydrochloride) inhibitor inhibit