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Anti-Carbonic Anhydrase 12 Antibody-PE (1H785)
🥰Excellent
Catalog No. TMAY-01031P
Anti-Carbonic Anhydrase 12 Antibody-PE (1H785) is a PE-conjugated Mouse antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody-PE (1H785) can be used in FCM.
Anti-Carbonic Anhydrase 12 Antibody-PE (1H785)
Anti-Carbonic Anhydrase 12 Antibody-PE (1H785)
🥰Excellent
Catalog No. TMAY-01031P
Anti-Carbonic Anhydrase 12 Antibody-PE (1H785) is a PE-conjugated Mouse antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody-PE (1H785) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Carbonic Anhydrase 12 Antibody-PE (1H785) is a PE-conjugated Mouse antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody-PE (1H785) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 1H785 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CA12 expression on MCF-7 cells. Cells were stained with PE-conjugated anti-Human CA12. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carbonic Anhydrase XII / CA12 (rh Carbonic Anhydrase XII / CA12; TMPY-00694; NP_001209.1; Met1-Gln291) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity. |
| Conjucates | PE |
| Others Formats | FITC |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human Carbonic Anhydrase XII / CA12 protein (TMPY-00694) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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