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Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody
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Catalog No. TMAC-02957
Alias p-MAPK14 (Thr180), p-MAPK14 (T180), MAPK14 (p-Thr180), MAPK14 (p-T180)
Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Thr180). Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody
Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody
😃Good
Catalog No. TMAC-02957Alias p-MAPK14 (Thr180), p-MAPK14 (T180), MAPK14 (p-Thr180), MAPK14 (p-T180)
Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Thr180). Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody can be used in IHC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Thr180). Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody can be used in IHC,WB. |
| Synonyms | p-MAPK14 (Thr180), p-MAPK14 (T180), MAPK14 (p-Thr180), MAPK14 (p-T180) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from HT29 cells untreated or treated with UV using P38 MAPK (Phospho-Thr180) Antibody TMAC-02957. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using P38 MAPK (Phospho-Thr180) Antibody TMAC-02957 (left) or the same antibody preincubated with blocking peptide (right). 3. Western blot analysis of extracts from HL60 cells, treated with TNFa or calf intestinal phosphatase (CIP), using P38 MAPK (Phospho-Thr180) Antibody TMAC-02957. |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 180 (E-M-T(p)-G-Y ) derived from Human P38MAPK |
| Antigen Species | human |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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