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Anti-CAMKK2 Polyclonal Antibody
(Synonyms: CAMKKB, CaMKK beta, CAMKK 2, CAMKK, CaM KK beta, CaM kinase kinase beta, Calcium/calmodulin dependent protein kinase β, Calcium/calmodulin dependent protein kinase kinase 2, Calcium/calmodulin dependent protein kinase beta) Copy Product Info
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Synonyms: CAMKKB, CaMKK beta, CAMKK 2, CAMKK, CaM KK beta, CaM kinase kinase beta, Calcium/calmodulin dependent protein kinase β, Calcium/calmodulin dependent protein kinase kinase 2, Calcium/calmodulin dependent protein kinase beta
Catalog No. TMAB-00276 Copy Product Info
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Anti-CAMKK2 Polyclonal Antibody is a Rabbit antibody targeting CAMKK2. Anti-CAMKK2 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-CAMKK2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CAMKK2 Polyclonal Antibody is a Rabbit antibody targeting CAMKK2. Anti-CAMKK2 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | CAMKKB, CaMKK beta, CAMKK 2, CAMKK, CaM KK beta, CaM kinase kinase beta, Calcium/calmodulin dependent protein kinase β, Calcium/calmodulin dependent protein kinase kinase 2, Calcium/calmodulin dependent protein kinase beta |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Cell projection. Note=Predominantly nuclear in unstimulated cells. Found in the cytoplasm and neurites after forskolin induction. |
| Tissue Specificity | Ubiquitously expressed with higher levels in the brain. Intermediate levels are detected in spleen, prostate, thyroid and leukocytes. The lowest level is in lung. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human CAMKK2 |
| Antigen Species | Human |
| Gene Name | CAMKK2 |
| Gene ID | |
| Protein Name | Calcium/calmodulin-dependent protein kinase kinase 2 |
| Uniprot ID | |
| Biology Area | MAPK pathway,MAPK Pathway,Calmodulin Pathway |
| Function | Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals. Seems to be involved in hippocampal activation of CREB1. May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching. |
| Molecular Weight | Theoretical: 55 kDa. Actual: 70 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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