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Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459)
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Catalog No. TMAY-02179F
Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459) is a FITC-conjugated Mouse antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459) can be used in FCM.
Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459)
Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459)
🥰Excellent
Catalog No. TMAY-02179F
Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459) is a FITC-conjugated Mouse antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459) can be used in FCM.
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| Description | Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459) is a FITC-conjugated Mouse antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody-FITC (7P459) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 7P459 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human B2M / Beta-2-microglobulin expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human B2M / Beta-2-microglobulin. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Beta-2 microglobulin/B2M (rh Beta-2 microglobulin/B2M; TMPY-01686; NP_004039.1; Met1-Met119) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | B2M, also known as β2-Microglobulin or CDABP0092, is a component of MHC class I molecules found expression in all nucleated cells (excludes red blood cells). The major function of MHC class I moleculesis is to display fragments of proteins from within the cell to T-cells and cells containing foreign proteins will be attacked. B2M (β2-Microglobulin) is a low molecular weight protein. It was demonstrated that B2M (β2-Microglobulin) was localized in the membranes of nucleated cells and was found to be associated with HL-A antigens. B2M (β2- Microglobulin) is present in free form in various body fluids and as a subunit of histocompatibility antigens on cell surfaces lateral to the α3 chain. Unlike α3, β2 has no transmembrane region. Directly above β2 lies the α1 chain, which itself is lateral to the α2. In the absence of B2M (β2 microglobulin), very limited amounts of MHC class I (classical and non-classical) molecules can be detected on the surface. In the absence of MHC class I, CD8 T cells, a subset of T cells involved in the development of acquired immunity cannot develop. Low levels of B2M (β2 microglobulin) can indicate non-progression of HIV. |
| Conjucates | FITC |
| Others Formats | Unconjugated/HRP |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human Beta-2 microglobulin/B2M Protein (TMPY-01686) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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