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Anti-TRP1 Antibody (9T409)
😃Good
Catalog No. TMAC-04140
Alias TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN
Anti-TRP1 Antibody (9T409) is a Rabbit antibody targeting TRP1. Anti-TRP1 Antibody (9T409) can be used in WB,ICC,IHC,IP.
Anti-TRP1 Antibody (9T409)
Anti-TRP1 Antibody (9T409)
😃Good
Catalog No. TMAC-04140Alias TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN
Anti-TRP1 Antibody (9T409) is a Rabbit antibody targeting TRP1. Anti-TRP1 Antibody (9T409) can be used in WB,ICC,IHC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-TRP1 Antibody (9T409) is a Rabbit antibody targeting TRP1. Anti-TRP1 Antibody (9T409) can be used in WB,ICC,IHC,IP. |
| Synonyms | TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN |
| Ig Type | IgG |
| Clone | 9T409 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of TRP1 on melanoma tissue lysate using anti-TRP1 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-TRP1 antibody. Counter stained with hematoxylin. 3. ICC staining TRP1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining TRP1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-100; IP: 1:10-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Tyrosinase (TYR), a type I membrane protein and copper-containing enzyme, is involved in the production of melanin, the primary pigment found in vertebrates. Melanin biogenesis requires the enzymatic activity of TYR, which catalyzes the critical and rate-limiting step of tyrosine hydroxylation in the biosynthesis of melanin. Defects effecting TYR activity result in various forms of albinism. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteine-rich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exists as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 72 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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