Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc)

1. Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 1-8 ng/mL. 2. Immobilized Mouse IFNAR1 His at 2 μg/mL (100 μL/well) can bind Mouse Interferon alpha 2/IFNA2 hFc , the EC50 of Mouse Interferon alpha 2/IFNA2 hFc is 10-80 ng/mL.

Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P01573.

Mouse

HEK293 Cells

> 88 % as determined by SDS-PAGE

IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.