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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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can be highly customized!
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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
NF-κB
PI3K
Reactive Oxygen Species
COX
VEGFR
PDGFR
Endogenous Metabolite
MMP
p38 MAPK
Antioxidant
mTOR
Akt
ERK
Wnt/beta-catenin
Antibacterial
AMPK
TNF
Raf
TGF-beta/Smad
GSK-3
c-Kit
CDK
JNK
FGFR
Ras
MEK
FLT
IκB/IKK
Src
DNA-PK
IL Receptor
MAPK
Parasite
EGFR
CFTR
S6 Kinase
Antibiotic
ALK
ATM/ATR
STAT
Ferroptosis
Caspase
JAK
NO Synthase
Mitophagy
HIV Protease
Antifungal
Calcium Channel
RIP kinase
NOD
Bcr-Abl
Hedgehog/Smoothened
Influenza Virus
Aurora Kinase
PDK
PPAR
Cytochromes P450
c-Met/HGFR
PKC
DNA/RNA Synthesis
ROS
Lipoxygenase
c-RET
IRAK
Interleukin
Bcl-2 Family
Mitochondrial Metabolism
Nrf2
PKA
Rho
PDE
Potassium Channel
NOD-like Receptor (NLR)
NOS
Dehydrogenase
Virus Protease
Tyrosine Kinases
IGF-1R
Casein Kinase
c-Fms
ROCK
Topoisomerase
Beta Amyloid
Tyrosinase
MLK
Cholinesterase (ChE)
P-gp
Prostaglandin Receptor
Trk receptor
PI4K
AChR
FAK
HIF/HIF Prolyl-Hydroxylase
Kras
HSV
PGE Synthase
TLR
HDAC
Syk
p53
NADPH
Glutathione Peroxidase
Adrenergic Receptor
E1/E2/E3 Enzyme
Smo
Chk
GABA Receptor
Sodium Channel
Chloride channel
ATPase
HCV Protease
Integrin
BACE
RAAS
Phosphatase
Serine Protease
TRP/TRPV Channel
Drug Metabolite
Glucosidase
PTEN
Epigenetic Reader Domain
MNK
Antiviral
SARS-CoV
Proteasome
GPCR
Carbonic Anhydrase
Transferase
Estrogen/progestogen Receptor
Adenosine Receptor
Tie-2
TOPK
Estrogen Receptor/ERR
PARP
CSF-1R
SIK
HSP
Porcupine
Free radical scavengers
Ephrin Receptor
transporter
ASK
Ligand for E3 Ligase
LPA Receptor
ribosome
Phospholipase
5-HT Receptor
Anti-infection
TAM Receptor
Monoamine Oxidase
S1P Receptor
HER
LPL Receptor
Reductase
GTPase
c-Myc
MRP
HBV
Serine/threonin kinase
Aryl Hydrocarbon Receptor
IAP
Immunology/Inflammation related
LDL
Molecular Glues
Opioid Receptor
CCR
LRRK2
Retinoid Receptor
KLF
PLK
HIF
SGK
NADPH-oxidase
Microtubule Associated
Mdm2
Proton pump
LTR
Histamine Receptor
Cysteine Protease
Leukotriene Receptor
FXR
RANKL/RANK
MAO
Glucocorticoid Receptor
IRE1
UGT
Gamma-secretase
DNA gyrase
Antifection
DNA Alkylation
ACK1
CaMK
Lipid
Beta-Secretase
Aminopeptidase
Sirtuin
PAI-1
MELK
Cannabinoid Receptor
Gap Junction Protein
AhR
BTK
FOXO3
PROTACs
Adenylyl Cyclase
GSNOR
NPC1L1
Monocarboxylate transporter
RAR/RXR
DHFR
Dopamine Receptor
ROR
Histone Methyltransferase
Dynamin
MyD88
Arginase
YAP
IFNAR
DYRK
Histone Demethylase
PERK
gp120/CD4
Galectin
N-Acetylglucosaminyltransferase
Cholecystokinin Receptor
AAK1
Hck
Cell Cycle Arrest
Liver X Receptor
PYK2
Amylase
iGluR
Myosin
Haspin Kinase
P2X Receptor
ABC Transporter
Anion Exchanger
Guanylate cyclase
Fatty Acid Synthase
PAK
FAAH
Somatostatin
PAD
cAMP
GluR
DNA
DUB
Indoleamine 2,3-Dioxygenase (IDO)
SGLT
ATP Citrate Lyase
BCRP
OXPHOS
Glutathione reductase
Acyltransferase
STING
Histone Acetyltransferase
Decarboxylase
cGAS
Pyroptosis
RSV
Methionine Adenosyltransferase (MAT)
Hippo pathway
GST
GPX
Reverse Transcriptase
Aromatase
CRISPR/Cas9
Hydroxylase
Adenosine Deaminase
Discoidin Domain Receptor (DDR)
Platelet aggregation
BMI-1
Thrombin
PD-1/PD-L1
PKM
ADC Cytotoxin

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