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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
Reactive Oxygen Species
COX
VEGFR
PDGFR
Endogenous Metabolite
p38 MAPK
MMP
Antioxidant
Akt
mTOR
ERK
AMPK
Wnt/beta-catenin
Antibacterial
TNF
Raf
TGF-beta/Smad
GSK-3
c-Kit
CDK
JNK
FGFR
Ras
MEK
FLT
IκB/IKK
Src
MAPK
DNA-PK
IL Receptor
Parasite
CFTR
EGFR
S6 Kinase
Antibiotic
ALK
ATM/ATR
STAT
Caspase
Ferroptosis
NO Synthase
JAK
Mitophagy
RIP kinase
HIV Protease
NOD
Antifungal
Calcium Channel
Hedgehog/Smoothened
Influenza Virus
Bcr-Abl
PDK
Aurora Kinase
Cytochromes P450
PPAR
c-Met/HGFR
DNA/RNA Synthesis
PKC
c-RET
IRAK
Lipoxygenase
ROS
Interleukin
Nrf2
Bcl-2 Family
Mitochondrial Metabolism
NOD-like Receptor (NLR)
PDE
PKA
Potassium Channel
Rho
IGF-1R
NOS
Casein Kinase
c-Fms
Dehydrogenase
Tyrosine Kinases
Virus Protease
Beta Amyloid
MLK
ROCK
Topoisomerase
Tyrosinase
Cholinesterase (ChE)
HIF/HIF Prolyl-Hydroxylase
PI4K
Prostaglandin Receptor
Trk receptor
Kras
AChR
FAK
HDAC
HSV
p53
PGE Synthase
P-gp
Syk
TLR
Adrenergic Receptor
Chk
Glutathione Peroxidase
NADPH
Smo
Sodium Channel
Antiviral
ATPase
BACE
Chloride channel
Drug Metabolite
E1/E2/E3 Enzyme
Epigenetic Reader Domain
GABA Receptor
Glucosidase
HCV Protease
Integrin
MNK
Phosphatase
PTEN
Serine Protease
TRP/TRPV Channel
5-HT Receptor
Adenosine Receptor
Anti-infection
ASK
Carbonic Anhydrase
CSF-1R
Ephrin Receptor
Estrogen Receptor/ERR
Estrogen/progestogen Receptor
Free radical scavengers
GPCR
HER
HSP
Ligand for E3 Ligase
LPA Receptor
Monoamine Oxidase
Opioid Receptor
PARP
Phospholipase
Porcupine
Proteasome
RAAS
ribosome
S1P Receptor
SARS-CoV
SIK
TAM Receptor
Tie-2
TOPK
Transferase
transporter
Aryl Hydrocarbon Receptor
CCR
c-Myc
GTPase
HBV
HIF
IAP
Immunology/Inflammation related
KLF
LDL
LPL Receptor
LRRK2
Microtubule Associated
Molecular Glues
MRP
NADPH-oxidase
PLK
Reductase
Retinoid Receptor
Serine/threonin kinase
SGK
ACK1
AhR
Aminopeptidase
Antifection
Beta-Secretase
CaMK
Cannabinoid Receptor
Cysteine Protease
DNA Alkylation
DNA gyrase
FXR
Gamma-secretase
Gap Junction Protein
Glucocorticoid Receptor
Histamine Receptor
IRE1
Leukotriene Receptor
Lipid
LTR
MAO
Mdm2
MELK
PAI-1
Proton pump
RANKL/RANK
Sirtuin
UGT
BTK
FOXO3
AAK1
ABC Transporter
Acyltransferase
Adenosine Deaminase
Adenylyl Cyclase
Amylase
Anion Exchanger
Arginase
Aromatase
ATP Citrate Lyase
BCRP
BMI-1
cAMP
Cell Cycle Arrest
cGAS
Cholecystokinin Receptor
CRISPR/Cas9
Decarboxylase
DHFR
Discoidin Domain Receptor (DDR)
DNA
Dopamine Receptor
DUB
Dynamin
DYRK
FAAH
Fatty Acid Synthase
Galectin
GluR
Glutathione reductase
gp120/CD4
GPX
GSNOR
GST
Guanylate cyclase
Haspin Kinase
Hck
Hippo pathway
Histone Acetyltransferase
Histone Demethylase
Histone Methyltransferase
Hydroxylase
IFNAR
iGluR
Indoleamine 2,3-Dioxygenase (IDO)
Liver X Receptor
Methionine Adenosyltransferase (MAT)
Monocarboxylate transporter
MyD88
Myosin
N-Acetylglucosaminyltransferase
Necroptosis
NPC1L1
OXPHOS
P2X Receptor
PAD
PAK
PD-1/PD-L1
PERK
PKM
Platelet aggregation
PROTACs
PYK2
Pyroptosis
RAR/RXR
Reverse Transcriptase
ROR
RSV
SGLT
Somatostatin
STING
Thrombin
YAP
ADC Cytotoxin

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