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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
ROS
Reactive Oxygen Species
COX
Endogenous Metabolite
VEGFR
Ras
p38 MAPK
Antibacterial
ERK
Akt
PDGFR
MMP
mTOR
Wnt/beta-catenin
TNF
Antioxidant
AMPK
TGF-beta/Smad
Raf
GSK-3
JNK
c-Kit
CDK
FGFR
MEK
FLT
Parasite
Interleukin
IκB/IKK
Caspase
NO Synthase
Src
MAPK
EGFR
IL Receptor
DNA/RNA Synthesis
STAT
DNA-PK
Antibiotic
CFTR
S6 Kinase
Ferroptosis
ATM/ATR
PPAR
ALK
HIV Protease
Calcium Channel
Kras
Antifungal
NOD
Mitophagy
JAK
Nrf2
Bcl-2 Family
RIP kinase
Influenza Virus
Cytochromes P450
Bcr-Abl
Hedgehog/Smoothened
PDK
NOD-like Receptor (NLR)
PKC
c-Met/HGFR
Aurora Kinase
IRAK
c-RET
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
PDE
Virus Protease
Potassium Channel
Beta Amyloid
Lipoxygenase
PKA
IGF-1R
Casein Kinase
c-Fms
NOS
Dehydrogenase
Phosphatase
Rho
SARS-CoV
HSV
P-gp
Prostaglandin Receptor
Tyrosinase
MLK
Tyrosine Kinases
Cholinesterase (ChE)
FAK
PI4K
Topoisomerase
TLR
ROCK
Sodium Channel
Trk receptor
PARP
AChR
Drug Metabolite
Syk
PTEN
p53
TRP/TRPV Channel
Anti-infection
GABA Receptor
Tie-2
Glucosidase
Smo
Epigenetic Reader Domain
HSP
HDAC
PGE Synthase
Serine Protease
Chk
Glutathione Peroxidase
Adrenergic Receptor
Proteasome
Integrin
Estrogen Receptor/ERR
LPL Receptor
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
MNK
Chloride channel
HCV Protease
BACE
NADPH
RANKL/RANK
CaMK
Antiviral
Adenosine Receptor
c-Myc
MDM-2/p53
Reductase
Phospholipase
ATPase
E1/E2/E3 Enzyme
HER
Antifection
Immunology/Inflammation related
PLK
S1P Receptor
Serine/threonin kinase
Opioid Receptor
OXPHOS
Free radical scavengers
Pyroptosis
Transferase
Necroptosis
transporter
LPA Receptor
5-HT Receptor
Monoamine Oxidase
GPCR
Ephrin Receptor
ROS Kinase
PD-1/PD-L1
RAAS
TOPK
CSF-1R
SIK
TAM Receptor
Carbonic Anhydrase
PERK
IAP
glycosidase
Porcupine
ribosome
Estrogen/progestogen Receptor
UGT
Ligands for E3 Ligase
ASK
Microtubule Associated
KLF
Cysteine Protease
FXR
Leukotriene Receptor
Aryl Hydrocarbon Receptor
LRRK2
Retinoid Receptor
Cannabinoid Receptor
NADPH-oxidase
Molecular Glues
Lipid
SGK
GTPase
Histone Acetyltransferase
HIF
Beta-Secretase
HBV
CCR
MRP
Survivin
Aminopeptidase
Proton pump
MyD88
Prolyl Endopeptidase (PREP)
IRE1
LDL
DNA gyrase
FKBP
Glucocorticoid Receptor
SGLT
AhR
Mdm2
DYRK
Liver X Receptor
MAO
PAK
PAI-1
MELK
Gap Junction Protein
Histamine Receptor
DNA Alkylation
LTR
ATP Citrate Lyase
Hippo pathway
Histone Methyltransferase
PYK2
Adenylate cyclase
Fatty Acid Synthase
FOXO3
BTK
IKZF
ROR
Dynamin
Galectin
Cell Cycle Arrest
Haspin Kinase
DUB
GPCR19
RSV
Tight Junction Protein
Monocarboxylate transporter
RAR/RXR
Amylase
Guanylate cyclase
CXCR
STING
GPX
PKM
YAP
IFNAR
Hck
IDO
Na-K-Cl cotransporter
Stearoyl-CoA Desaturase (SCD)
ACK1
BMI-1
Thrombin
GSNOR
Y Box Binding Protein 1
Arginase
gp120/CD4
Photosensitizer
cAMP
AIM2
GST
Reverse Transcriptase
Aromatase
Platelet aggregation
NPC1L1
DHFR
Cholecystokinin Receptor
AAK1
Myosin
Glutathione reductase
Acyltransferase
Decarboxylase
Adenosine Deaminase
PROTACs
CD38
Histone Demethylase
N-Acetylglucosaminyltransferase
iGluR
ABC Transporter
Anion Exchanger
FAAH
GluR
DNA
Sirtuin
CD74
cGAS
Hydroxylase
Dopamine Receptor
P2X Receptor
Somatostatin
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
BCRP
Methionine Adenosyltransferase (MAT)
Cuproptosis
Discoidin Domain Receptor (DDR)
Kinesin
ADC Cytotoxin

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