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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
Reactive Oxygen Species
COX
VEGFR
Ras
Endogenous Metabolite
Antibacterial
p38 MAPK
PDGFR
Akt
MMP
Antioxidant
mTOR
ERK
Wnt/beta-catenin
AMPK
TNF
Raf
TGF-beta/Smad
GSK-3
c-Kit
CDK
JNK
FGFR
Parasite
FLT
MEK
IκB/IKK
Src
MAPK
DNA-PK
IL Receptor
Antibiotic
Caspase
S6 Kinase
CFTR
EGFR
NO Synthase
STAT
Ferroptosis
ATM/ATR
ALK
Mitophagy
Kras
Antifungal
HIV Protease
DNA/RNA Synthesis
RIP kinase
NOD
Calcium Channel
JAK
Interleukin
Influenza Virus
PPAR
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Bcr-Abl
Cytochromes P450
Bcl-2 Family
Nrf2
PDK
NOD-like Receptor (NLR)
c-Met/HGFR
Aurora Kinase
PKC
Lipoxygenase
IRAK
c-RET
Mitochondrial Metabolism
ROS
Casein Kinase
c-Fms
Potassium Channel
PDE
PKA
Virus Protease
HIF/HIF Prolyl-Hydroxylase
Rho
NOS
IGF-1R
Dehydrogenase
Tyrosinase
Tyrosine Kinases
Cholinesterase (ChE)
ROCK
Beta Amyloid
PI4K
Phosphatase
Topoisomerase
Prostaglandin Receptor
MLK
HSV
Trk receptor
P-gp
FAK
Anti-infection
Syk
GABA Receptor
Sodium Channel
PTEN
TLR
p53
Tie-2
Glucosidase
Smo
SARS-CoV
AChR
Drug Metabolite
PGE Synthase
HDAC
NADPH
TRP/TRPV Channel
Adrenergic Receptor
Serine Protease
Chk
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LPL Receptor
ATPase
BACE
Antiviral
transporter
Monoamine Oxidase
MNK
PARP
Chloride channel
HCV Protease
Integrin
Estrogen Receptor/ERR
HSP
Phospholipase
E1/E2/E3 Enzyme
Transferase
RANKL/RANK
LPA Receptor
5-HT Receptor
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
S1P Receptor
GPCR
Adenosine Receptor
c-Myc
Ephrin Receptor
MDM-2/p53
ROS Kinase
Opioid Receptor
OXPHOS
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Reductase
RAAS
TOPK
CSF-1R
SIK
Ligand for E3 Ligase
TAM Receptor
Estrogen/progestogen Receptor
UGT
Antifection
ASK
Carbonic Anhydrase
Porcupine
ribosome
HER
Necroptosis
Molecular Glues
Lipid
SGK
Immunology/Inflammation related
KLF
PLK
GTPase
Histone Acetyltransferase
HIF
Serine/threonin kinase
Leukotriene Receptor
FXR
Aryl Hydrocarbon Receptor
LDL
LRRK2
Pyroptosis
Retinoid Receptor
Cannabinoid Receptor
NADPH-oxidase
Beta-Secretase
MRP
Aminopeptidase
Microtubule Associated
HBV
IAP
CCR
Glucocorticoid Receptor
CaMK
SGLT
AhR
Mdm2
DYRK
Liver X Receptor
MAO
PAK
PAI-1
MELK
Gap Junction Protein
PD-1/PD-L1
Proton pump
Cysteine Protease
Prolyl Endopeptidase (PREP)
IRE1
DNA gyrase
FKBP
Histamine Receptor
Myosin
DNA Alkylation
PYK2
LTR
ATP Citrate Lyase
Sirtuin
Hippo pathway
FOXO3
BTK
IKZF
YAP
IFNAR
Hck
IDO
Na-K-Cl cotransporter
Stearoyl-CoA Desaturase (SCD)
ACK1
BMI-1
Thrombin
ROR
Dynamin
Galectin
Cell Cycle Arrest
Haspin Kinase
DUB
GPCR19
RSV
GSNOR
Y Box Binding Protein 1
Arginase
gp120/CD4
Photosensitizer
cAMP
AIM2
GST
Reverse Transcriptase
Aromatase
Platelet aggregation
Monocarboxylate transporter
RAR/RXR
MyD88
Amylase
Guanylate cyclase
STING
GPX
PKM
NPC1L1
DHFR
Cholecystokinin Receptor
AAK1
Glutathione reductase
Acyltransferase
Decarboxylase
Adenosine Deaminase
Adenylyl Cyclase
Dopamine Receptor
Histone Methyltransferase
P2X Receptor
Fatty Acid Synthase
Somatostatin
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
BCRP
Survivin
Methionine Adenosyltransferase (MAT)
Cuproptosis
Discoidin Domain Receptor (DDR)
PROTACs
CD38
Histone Demethylase
PERK
N-Acetylglucosaminyltransferase
iGluR
ABC Transporter
Anion Exchanger
FAAH
GluR
DNA
cGAS
CRISPR/Cas9
Hydroxylase
ADC Cytotoxin

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