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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
Reactive Oxygen Species
COX
VEGFR
Ras
Endogenous Metabolite
p38 MAPK
Antibacterial
PDGFR
Akt
MMP
Antioxidant
ERK
mTOR
Wnt/beta-catenin
AMPK
TNF
Raf
TGF-beta/Smad
GSK-3
c-Kit
CDK
JNK
FGFR
Parasite
FLT
MEK
IκB/IKK
Src
DNA-PK
Caspase
MAPK
IL Receptor
Antibiotic
NO Synthase
S6 Kinase
CFTR
EGFR
Ferroptosis
Interleukin
ATM/ATR
STAT
Mitophagy
ALK
Kras
HIV Protease
Antifungal
RIP kinase
JAK
DNA/RNA Synthesis
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Bcl-2 Family
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NOD
PPAR
Bcr-Abl
Hedgehog/Smoothened
Nrf2
Aurora Kinase
PDK
c-Met/HGFR
NOD-like Receptor (NLR)
PKC
ROS
Lipoxygenase
c-RET
IRAK
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
Casein Kinase
NOS
Virus Protease
PKA
PDE
c-Fms
Potassium Channel
Dehydrogenase
Rho
IGF-1R
Tyrosine Kinases
Cholinesterase (ChE)
Tyrosinase
Phosphatase
ROCK
Topoisomerase
HSV
Prostaglandin Receptor
Beta Amyloid
PI4K
MLK
PARP
P-gp
Trk receptor
FAK
Tie-2
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Glucosidase
Smo
PTEN
Epigenetic Reader Domain
PGE Synthase
SARS-CoV
TLR
HDAC
GABA Receptor
AChR
Syk
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p53
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LPL Receptor
NADPH
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Chk
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HCV Protease
Integrin
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Estrogen Receptor/ERR
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Antifection
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transporter
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OXPHOS
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ASK
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ribosome
5-HT Receptor
MDM-2/p53
TAM Receptor
ROS Kinase
HER
S1P Receptor
Necroptosis
GTPase
MRP
HBV
Serine/threonin kinase
Leukotriene Receptor
FXR
Aryl Hydrocarbon Receptor
Immunology/Inflammation related
LDL
Molecular Glues
CCR
Lipid
Beta-Secretase
LRRK2
Aminopeptidase
Histone Acetyltransferase
Pyroptosis
Retinoid Receptor
KLF
PLK
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SGK
Cannabinoid Receptor
NADPH-oxidase
Microtubule Associated
Mdm2
Proton pump
Histone Methyltransferase
LTR
DYRK
PERK
Histamine Receptor
Cysteine Protease
Liver X Receptor
PYK2
MAO
Glucocorticoid Receptor
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Myosin
IRE1
DNA gyrase
DNA Alkylation
PAK
CaMK
SGLT
ATP Citrate Lyase
Survivin
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PAI-1
MELK
Hippo pathway
FKBP
Gap Junction Protein
AhR
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BTK
IKZF
FOXO3
PROTACs
Adenylyl Cyclase
GSNOR
NPC1L1
Monocarboxylate transporter
RAR/RXR
CD38
DHFR
Dopamine Receptor
ROR
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MyD88
Y Box Binding Protein 1
YAP
Arginase
IFNAR
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gp120/CD4
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AAK1
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Amylase
IDO
iGluR
Haspin Kinase
P2X Receptor
ABC Transporter
Na-K-Cl cotransporter
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PAD
cAMP
GluR
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Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
BCRP
Glutathione reductase
Acyltransferase
STING
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GST
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Reverse Transcriptase
Aromatase
CRISPR/Cas9
Hydroxylase
Adenosine Deaminase
Cuproptosis
Discoidin Domain Receptor (DDR)
Platelet aggregation
BMI-1
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PKM
ADC Cytotoxin

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