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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
ROS
Reactive Oxygen Species
COX
Endogenous Metabolite
VEGFR
Ras
p38 MAPK
Antibacterial
ERK
Akt
PDGFR
MMP
mTOR
Wnt/beta-catenin
Antioxidant
TNF
AMPK
TGF-beta/Smad
Raf
GSK-3
JNK
c-Kit
CDK
FGFR
MEK
Parasite
FLT
IκB/IKK
Interleukin
Caspase
NO Synthase
Src
MAPK
DNA/RNA Synthesis
STAT
DNA-PK
Antibiotic
IL Receptor
EGFR
CFTR
S6 Kinase
Ferroptosis
ATM/ATR
HIV Protease
Mitophagy
Calcium Channel
Antifungal
PPAR
Kras
ALK
RIP kinase
Bcl-2 Family
Nrf2
JAK
Influenza Virus
Cytochromes P450
Bcr-Abl
NOD
Hedgehog/Smoothened
PDK
NOD-like Receptor (NLR)
PKC
Aurora Kinase
c-Met/HGFR
c-RET
IRAK
PDE
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
Virus Protease
Lipoxygenase
PKA
Potassium Channel
IGF-1R
Casein Kinase
Dehydrogenase
Beta Amyloid
NOS
c-Fms
Phosphatase
SARS-CoV
HSV
Rho
P-gp
Prostaglandin Receptor
Tyrosinase
MLK
Tyrosine Kinases
Cholinesterase (ChE)
FAK
ROCK
Topoisomerase
TLR
AChR
PI4K
Sodium Channel
Trk receptor
Drug Metabolite
PARP
GABA Receptor
TRP/TRPV Channel
Anti-infection
PTEN
p53
Tie-2
Glucosidase
Smo
Epigenetic Reader Domain
HSP
Syk
HDAC
PGE Synthase
NADPH
Adrenergic Receptor
Glutathione Peroxidase
Proteasome
Integrin
Estrogen Receptor/ERR
Serine Protease
Chk
ATPase
LPL Receptor
BACE
RANKL/RANK
CaMK
Antiviral
Chloride channel
HCV Protease
Reductase
Phospholipase
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
MNK
PERK
E1/E2/E3 Enzyme
Antifection
Adenosine Receptor
c-Myc
MDM-2/p53
Transferase
Necroptosis
transporter
LPA Receptor
5-HT Receptor
Monoamine Oxidase
Serine/threonin kinase
Opioid Receptor
OXPHOS
Free radical scavengers
Pyroptosis
RAAS
TOPK
CSF-1R
SIK
Ligand for E3 Ligase
TAM Receptor
Immunology/Inflammation related
PLK
S1P Receptor
Carbonic Anhydrase
IAP
glycosidase
Porcupine
ribosome
HER
Estrogen/progestogen Receptor
UGT
ASK
Microtubule Associated
GPCR
Ephrin Receptor
ROS Kinase
PD-1/PD-L1
Molecular Glues
Lipid
SGK
Cysteine Protease
Leukotriene Receptor
FXR
Aryl Hydrocarbon Receptor
LRRK2
Retinoid Receptor
Cannabinoid Receptor
NADPH-oxidase
Beta-Secretase
KLF
HBV
CCR
MRP
Survivin
Aminopeptidase
GTPase
Histone Acetyltransferase
HIF
Glucocorticoid Receptor
SGLT
AhR
Proton pump
MyD88
Prolyl Endopeptidase (PREP)
IRE1
LDL
DNA gyrase
FKBP
Histamine Receptor
Myosin
DNA Alkylation
LTR
ATP Citrate Lyase
Sirtuin
Hippo pathway
Histone Methyltransferase
PYK2
Fatty Acid Synthase
Mdm2
DYRK
Liver X Receptor
MAO
PAK
PAI-1
MELK
Gap Junction Protein
FOXO3
IKZF
BTK
YAP
IFNAR
Hck
IDO
Na-K-Cl cotransporter
Stearoyl-CoA Desaturase (SCD)
ACK1
BMI-1
Thrombin
Monocarboxylate transporter
RAR/RXR
Amylase
Guanylate cyclase
CXCR
STING
GPX
PKM
NPC1L1
DHFR
Cholecystokinin Receptor
AAK1
Glutathione reductase
Acyltransferase
Decarboxylase
Adenosine Deaminase
ROR
Dynamin
Galectin
Cell Cycle Arrest
Haspin Kinase
DUB
GPCR19
RSV
Tight Junction Protein
PROTACs
CD38
Histone Demethylase
N-Acetylglucosaminyltransferase
iGluR
ABC Transporter
Anion Exchanger
FAAH
GluR
DNA
CD74
cGAS
Hydroxylase
Adenylyl Cyclase
Dopamine Receptor
P2X Receptor
Somatostatin
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
BCRP
Methionine Adenosyltransferase (MAT)
Cuproptosis
Discoidin Domain Receptor (DDR)
Kinesin
GSNOR
Y Box Binding Protein 1
Arginase
gp120/CD4
Photosensitizer
cAMP
AIM2
GST
Reverse Transcriptase
Aromatase
Platelet aggregation
ADC Cytotoxin

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