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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
ROS
Reactive Oxygen Species
COX
Endogenous Metabolite
VEGFR
Ras
p38 MAPK
Antibacterial
ERK
Akt
PDGFR
MMP
mTOR
Wnt/beta-catenin
TNF
Antioxidant
AMPK
TGF-beta/Smad
Raf
GSK-3
JNK
c-Kit
CDK
FGFR
MEK
FLT
Parasite
Interleukin
IκB/IKK
Caspase
Src
NO Synthase
EGFR
MAPK
DNA/RNA Synthesis
STAT
IL Receptor
DNA-PK
Antibiotic
CFTR
S6 Kinase
Ferroptosis
Calcium Channel
ATM/ATR
ALK
HIV Protease
Nrf2
Antifungal
PPAR
Mitophagy
JAK
Kras
Bcl-2 Family
NOD
RIP kinase
Influenza Virus
Cytochromes P450
Bcr-Abl
NOD-like Receptor (NLR)
Hedgehog/Smoothened
PDK
PKC
c-Met/HGFR
Aurora Kinase
IRAK
Virus Protease
PDE
Mitochondrial Metabolism
Potassium Channel
HIF/HIF Prolyl-Hydroxylase
c-RET
IGF-1R
Casein Kinase
Beta Amyloid
Lipoxygenase
PKA
NOS
c-Fms
HSV
Cholinesterase (ChE)
Dehydrogenase
Rho
Phosphatase
SARS-CoV
Tyrosine Kinases
FAK
P-gp
Prostaglandin Receptor
TLR
Tyrosinase
MLK
ROCK
Sodium Channel
Topoisomerase
PI4K
Drug Metabolite
Trk receptor
AChR
HDAC
TRP/TRPV Channel
Anti-infection
PARP
GABA Receptor
PGE Synthase
PTEN
Syk
Tie-2
Glucosidase
HSP
Adrenergic Receptor
LPL Receptor
Glutathione Peroxidase
p53
Serine Protease
Chk
Integrin
Estrogen Receptor/ERR
Smo
Epigenetic Reader Domain
ATPase
E1/E2/E3 Enzyme
HER
BACE
NADPH
RANKL/RANK
CaMK
Antiviral
Adenosine Receptor
MDM-2/p53
Antifection
Chloride channel
HCV Protease
Opioid Receptor
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
MNK
Proteasome
Reductase
Phospholipase
Carbonic Anhydrase
PERK
IAP
glycosidase
Porcupine
ribosome
Transferase
Necroptosis
transporter
LPA Receptor
5-HT Receptor
Monoamine Oxidase
GPCR
BTK
Ephrin Receptor
PD-1/PD-L1
Estrogen/progestogen Receptor
UGT
Ligands for E3 Ligase
ASK
Microtubule Associated
Serine/threonin kinase
OXPHOS
Free radical scavengers
Pyroptosis
Immunology/Inflammation related
PLK
S1P Receptor
TOPK
CSF-1R
SIK
TAM Receptor
HBV
CCR
GluR
Molecular Glues
Lipid
SGK
GTPase
c-Myc
Histone Acetyltransferase
HIF
ROS Kinase
MRP
Survivin
Aminopeptidase
Cysteine Protease
FXR
Leukotriene Receptor
Aryl Hydrocarbon Receptor
LRRK2
Retinoid Receptor
Cannabinoid Receptor
NADPH-oxidase
KLF
RAAS
Beta-Secretase
LTR
ATP Citrate Lyase
Hippo pathway
Glucocorticoid Receptor
SGLT
AhR
Mdm2
DYRK
Liver X Receptor
MAO
PAK
PAI-1
MELK
Gap Junction Protein
Histone Methyltransferase
PYK2
Adenylate cyclase
Fatty Acid Synthase
Methionine Adenosyltransferase (MAT)
Proton pump
MyD88
Prolyl Endopeptidase (PREP)
IRE1
LDL
DNA gyrase
FKBP
Histamine Receptor
DNA Alkylation
IKZF
PROTACs
CD38
Histone Demethylase
N-Acetylglucosaminyltransferase
iGluR
ABC Transporter
Anion Exchanger
FAAH
DNA
Sirtuin
CD74
cGAS
Hydroxylase
YAP
IFNAR
OCT
Hck
IDO
Stearoyl-CoA Desaturase (SCD)
ACK1
FOXO3
BMI-1
Thrombin
GSNOR
Y Box Binding Protein 1
Arginase
gp120/CD4
Photosensitizer
cAMP
AIM2
GST
Reverse Transcriptase
Aromatase
Platelet aggregation
Dopamine Receptor
P2X Receptor
Somatostatin
PAD
Androgen Receptor
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
Cuproptosis
Discoidin Domain Receptor (DDR)
Kinesin
Monocarboxylate transporter
RAR/RXR
Amylase
Guanylate cyclase
CXCR
STING
GPX
PKM
ROR
Dynamin
Galectin
Cell Cycle Arrest
Haspin Kinase
DPP-4
DUB
GPCR19
RSV
Tight Junction Protein
NPC1L1
DHFR
Cholecystokinin Receptor
AAK1
Myosin
Glutathione reductase
Acyltransferase
Decarboxylase
Adenosine Deaminase
ADC Cytotoxin
FOXO

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