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Anti-C5AR1 Polyclonal Antibody
😃Good
Catalog No. TMAB-00263
Alias CD88, C5R1, C5AR1, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)
Anti-C5AR1 Polyclonal Antibody is a Rabbit antibody targeting C5AR1. Anti-C5AR1 Polyclonal Antibody can be used in WB.
Anti-C5AR1 Polyclonal Antibody
Anti-C5AR1 Polyclonal Antibody
😃Good
Catalog No. TMAB-00263Alias CD88, C5R1, C5AR1, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)
Anti-C5AR1 Polyclonal Antibody is a Rabbit antibody targeting C5AR1. Anti-C5AR1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-C5AR1 Polyclonal Antibody is a Rabbit antibody targeting C5AR1. Anti-C5AR1 Polyclonal Antibody can be used in WB. |
| Alias | CD88, C5R1, C5AR1, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR) |
| Ig Type | IgG |
| Reactivity | Human (predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep,GuineaPig) |
| Verified Activity | Protein: k562 (human) lysate at 40 μg; Primary: rabbit Anti-C5R1 (TMAB-00263) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit Igg (secondary antibody) at 1: 5000; Predicted band size: 39 kDa Observed band size: 36 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | CD88, also known as C5a receptor (C5aR), is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants. |
| Immunogen | KLH conjugated synthetic peptide: human C5R1 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | MAC,Vitamins / minerals,Vitamins / Minerals,GPCR |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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