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Anti-CD8 alpha Antibody (1T746)
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Catalog No. TMAC-00737
Alias p32, OKT8 T-cell antigen, MAL, Lyt-2, Leu2, CD8a molecule, CD8a, CD8 α/CD8A, CD8
Anti-CD8 alpha Antibody (1T746) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (1T746) can be used in WB,ICC/IF,IHC.
Anti-CD8 alpha Antibody (1T746)
Anti-CD8 alpha Antibody (1T746)
😃Good
Catalog No. TMAC-00737Alias p32, OKT8 T-cell antigen, MAL, Lyt-2, Leu2, CD8a molecule, CD8a, CD8 α/CD8A, CD8
Anti-CD8 alpha Antibody (1T746) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (1T746) can be used in WB,ICC/IF,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Product Introduction
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Chemical Properties
| Description | Anti-CD8 alpha Antibody (1T746) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (1T746) can be used in WB,ICC/IF,IHC. |
| Synonyms | p32, OKT8 T-cell antigen, MAL, Lyt-2, Leu2, CD8a molecule, CD8a, CD8 α/CD8A, CD8 |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of CD8 alpha on different lysates using anti-CD8 alpha antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Lovo. 2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD8 alpha antibody. Counter stained with hematoxylin. 3. ICC staining CD8 alpha in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining CD8 alpha in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The T cell receptor (TCR) is a heterodimer composed of either α and β or γ and δ chains. CD3 chains and the CD4 or CD8 (CD8-α and CD8-β) co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8 proteins; T helper cells express CD4 proteins and T cytotoxic cells display CD8 proteins. CD8s are cell surface glycoproteins that exist as two chain complex (αα or αβ) receptors that bind class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 proteins is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 26 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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