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Anti-CD83 Antibody-APC (3W245)

🥰Excellent
Catalog No. TMAY-03408A

Anti-CD83 Antibody-APC (3W245) is a APC-conjugated Rabbit antibody targeting CD83. Anti-CD83 Antibody-APC (3W245) can be used in FCM.

Anti-CD83 Antibody-APC (3W245)

Anti-CD83 Antibody-APC (3W245)

🥰Excellent
Catalog No. TMAY-03408A
Anti-CD83 Antibody-APC (3W245) is a APC-conjugated Rabbit antibody targeting CD83. Anti-CD83 Antibody-APC (3W245) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CD83 Antibody-APC (3W245) is a APC-conjugated Rabbit antibody targeting CD83. Anti-CD83 Antibody-APC (3W245) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
3W245
Reactivity
Mouse
Verified Activity
Flow cytometric analysis of Mouse CD83 expression on LPS-stimulated BABL/c splenocytes. Cells were stained with APC-conjugated anti-Mouse CD83. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD83 (rM CD83; TMPY-02156; O88324; Met1-Arg133) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Mouse CD83 Protein (TMPY-02156)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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