HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.

Pack Size	Availability	Price/USD	Quantity
100 μg	Inquiry	$ 734.00
1 mg	Inquiry	$ 4,899.00

Pack Size

Availability

Price/USD

Quantity

100 μg

Inquiry

$ 734.00

1 mg

Inquiry

$ 4,899.00

Description

Species	Human
Expression System	HEK293
Tag	C-His-Avi
Accession Number	AAA03604.1(HLA-A*02:03)&P61769(B2M)&FMNKFIYEI
Synonyms	Alpha-1-fetoprotein, HPAFP, AFPD, AFP, Alpha-feto, MHC, FETA, Alpha-fetoprotein
Construction	Recombinant PE-Labeled Human HLA-A02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A02:03&B2M&AFP (FMNKFIYEI) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin. It contains Gly25-Thr305(HLA-A02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide.[Accession \|AAA03604.1(HLA-A02:03)&P61769(B2M)&FMNKFIYEI]

Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability & Storage	Valid for 6 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.