Powder: -20°C for 3 years | In solvent: -80°C for 1 year
7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. It exhibited either alone or as hybrid with other active pharmacophores diverse pharmacological profiles. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake ( IC 50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC 50 s of 1.18 μM and 0.97 μM, respectively [1].
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Description | 7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. It exhibited either alone or as hybrid with other active pharmacophores diverse pharmacological profiles. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake ( IC 50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC 50 s of 1.18 μM and 0.97 μM, respectively [1]. |
Molecular Weight | 247.72 |
Formula | C13H14ClN3 |
CAS No. | 837-52-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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7-Chloro-4-(piperazin-1-yl)quinoline 837-52-5 Compound Fr13587 inhibitor inhibit