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Synonyms: TNC, TN, Tenascin-C (TN-C), Tenascin, Neuronectin, Myotendinous antigen, JI, HXB, Hexabrachion, GP 150-225, GMEM, Glioma-associated-extracellular matrix antigen, Cytotactin
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-Tenascin Polyclonal Antibody 2 is a Rabbit antibody targeting Tenascin. Anti-Tenascin Polyclonal Antibody 2 can be used in IF, IHC-Fr, IHC-P. |
| Synonyms | TNC, TN, Tenascin-C (TN-C), Tenascin, Neuronectin, Myotendinous antigen, JI, HXB, Hexabrachion, GP 150-225, GMEM, Glioma-associated-extracellular matrix antigen, Cytotactin |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Brain specific. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Tenascin, also known as hexabrachion and cytotactin, is an extracellular matrix protein with a spatially and temporally restricted tissue distribution. It is a hexameric, multidomain protein with disulfide linked subunits of 190 to 240 kD, originally characterized as 'myotendinous antigen.' In the embryo it is present in dense mesenchyme surrounding developing epithelia and in developing cartilage and bone. In the adult, tenascin remains present in tendons and myotendinous junctions in the perichondrium and periosteum, as well as in smooth muscle. |
| Immunogen | KLH conjugated synthetic peptide: human Tenascin C |
| Antigen Species | Human |
| Gene Name | TNC |
| Gene ID | |
| Protein Name | Tenascin |
| Uniprot ID | |
| Biology Area | ECM Proteins,Neural Signal Transduction,Secreted Molecules,Extracellular |
| Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. |
| Molecular Weight | Theoretical: 230 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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