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Antiproliferative agent-13

Name: Antiproliferative agent-13
Brand: TargetMol
SKU: T9974
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9974Cas No. 663214-48-0

Antiproliferative agent-13 is a compound with antiproliferative activity.

Antiproliferative agent-13

🥰Excellent

Purity: 99.723%

Catalog No. T9974Cas No. 663214-48-0

Antiproliferative agent-13 is a compound with antiproliferative activity.

Pack Size	Price	Availability
5 mg	$34	In Stock
10 mg	$58	In Stock
25 mg	$121	In Stock
50 mg	$191	In Stock
100 mg	$282	In Stock
200 mg	$401	In Stock
1 mL x 10 mM (in DMSO)	$37	In Stock

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Batch Information

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Purity:99.723%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Antiproliferative agent-13 is a compound with antiproliferative activity.
In vitro	qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line

Chemical Properties

Molecular Weight	382.37
Formula	C₂₀H₁₈N₂O₆
Cas No.	663214-48-0
Smiles	COc1cc(cc(OC)c1OC)C1C(C#N)=C(N)Oc2cc3OCOc3cc12

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (130.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6153 mL	13.0763 mL	26.1527 mL	130.7634 mL
5 mM	0.5231 mL	2.6153 mL	5.2305 mL	26.1527 mL
10 mM	0.2615 mL	1.3076 mL	2.6153 mL	13.0763 mL
20 mM	0.1308 mL	0.6538 mL	1.3076 mL	6.5382 mL
50 mM	0.0523 mL	0.2615 mL	0.5231 mL	2.6153 mL
100 mM	0.0262 mL	0.1308 mL	0.2615 mL	1.3076 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc