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4-Methoxybenzaldehyde

Name: 4-Methoxybenzaldehyde
Brand: TargetMol
SKU: T7910
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7910Cas No. 123-11-5

Alias P-Methoxybenzaldehyde, p-Anisaldehyde, Anisic aldehyde, Anisaldehyde, 4-Anisaldehyde

4-Methoxybenzaldehyde (p-Anisaldehyde) is a naturally occurring fragrant phenolic compound , it has significant antifungal activity against Candida, including azole-resistant strains.

4-Methoxybenzaldehyde

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Purity: 98.86%

Catalog No. T7910Alias P-Methoxybenzaldehyde, p-Anisaldehyde, Anisic aldehyde, Anisaldehyde, 4-AnisaldehydeCas No. 123-11-5

4-Methoxybenzaldehyde (p-Anisaldehyde) is a naturally occurring fragrant phenolic compound , it has significant antifungal activity against Candida, including azole-resistant strains.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:98.86%

Appearance:Liquid

Color:Transparent

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COA LCMS HNMR

Product Introduction

4-Methoxybenzaldehyde AI Summary

4-Methoxybenzaldehyde exhibits a broad spectrum of bioactivities, including inhibitory activity against mushroom tyrosinase with an IC50 of 320,000 nM, human cytochrome P450 1A2 with an IC50 of 270,000 nM, human cytochrome P450 2A6 with an IC50 of 5,150 nM, and mouse cytochrome P450 2A5 with an IC50 of 5,230 nM. It also inhibits Aldehyde Dehydrogenase 1 (ALDH1A1) with a potency of 7,943.3 nM, PTHR with 1,122.0 nM, and HP1-beta chromodomain interactions with methylated histone tails with 89,125.1 nM. Additionally, it acts as an agonist of thyroid hormone receptor beta signaling with a potency of 17,782.8 nM and as an antagonist of androgen receptor signaling with 56,234.1 nM, and peroxisome proliferator-activated receptor gamma signaling with 50,118.7 nM. 4-Methoxybenzaldehyde also exhibits estrogenic activity in human MVLN cells, thrips luring and acaricidal activities, antimicrobial activity against a range of pathogens, and protective activity against Daboia russellii venom-induced hemorrhage in Swiss albino mice. Notably, it shows significant inhibitory activity against SSADH and GABAT with IC50 values greater than 1,000,000 nM, indicating low potency for these enzymes. Moreover, it inhibits NO711 binding to mouse GAT1 expressed in HEK293 cell membranes, showing 98.0% activity at 1 uM, and also exhibits cytotoxicity against mouse B16F10 cells with an IC50 of 70,740 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	4-Methoxybenzaldehyde (p-Anisaldehyde) is a naturally occurring fragrant phenolic compound , it has significant antifungal activity against Candida, including azole-resistant strains.
Synonyms	P-Methoxybenzaldehyde, p-Anisaldehyde, Anisic aldehyde, Anisaldehyde, 4-Anisaldehyde

Chemical Properties

Molecular Weight	136.15
Formula	C₈H₈O₂
Cas No.	123-11-5
Smiles	COC1=CC=C(C=O)C=C1
Relative Density.	1.123. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (183.62 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (14.69 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.3448 mL	36.7242 mL	73.4484 mL	367.2420 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL	73.4484 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL	36.7242 mL
20 mM	0.3672 mL	1.8362 mL	3.6724 mL	18.3621 mL
50 mM	0.1469 mL	0.7345 mL	1.4690 mL	7.3448 mL
100 mM	0.0734 mL	0.3672 mL	0.7345 mL	3.6724 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc