Other Disease Modeling

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Disease Modeling

Cancer Modeling

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Cardiovascular System Disease Modeling

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Digestive System Disease Modeling

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Endocrinology and Metabolism Disease Modeling

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Genetically Engineered Disease Modeling

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Immunology and Inflammation Disease Modeling

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Nervous System Disease Modeling

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Other Disease Modeling

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Respiratory System Disease Modeling

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Skin Disease Modeling

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Urinary System Disease Modeling

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Other Disease Modeling

In addition to commonly studied systemic disease models, TargetMol also offers modeling products for infectious diseases, ophthalmic disorders, skeletal diseases, and reproductive system conditions. By utilizing various pharmacological agents and biological inducers, these products support researchers in establishing diverse experimental models, providing flexible solutions for the study of specialized diseases and the development of innovative therapeutics.

Busulfan

T092355-98-1

Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.

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Reserpine

T079150-55-5

Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.

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8-Epidiosbulbin E acetate

TN134291095-48-6

8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.

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N,N'-Dinitrosopiperazine

T81720140-79-4

N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is a carcinogen that targets the nasopharyngeal epithelium to promote nasopharyngeal carcinoma (NPC) metastasis by modulating various signaling pathways through protein phosphorylation, notably phosphorylating LYRIC at serine 568 [1].

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8-10 weeks

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