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Anti-CD46 Antibody-APC (8C827)
🥰Excellent
Catalog No. TMAY-02294A
Anti-CD46 Antibody-APC (8C827) is a APC-conjugated Mouse antibody targeting CD46. Anti-CD46 Antibody-APC (8C827) can be used in FCM.
Anti-CD46 Antibody-APC (8C827)
Anti-CD46 Antibody-APC (8C827)
🥰Excellent
Catalog No. TMAY-02294A
Anti-CD46 Antibody-APC (8C827) is a APC-conjugated Mouse antibody targeting CD46. Anti-CD46 Antibody-APC (8C827) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD46 Antibody-APC (8C827) is a APC-conjugated Mouse antibody targeting CD46. Anti-CD46 Antibody-APC (8C827) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8C827 |
| Reactivity | Human |
| Verified Activity | Profile of anti-CD46 reactivity on HeLa cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; TMPY-02023; EAW93471.1; Met 1-Asp 328) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD46 protein (TMPY-02023) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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