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Anti-PSMA Antibody (1I379) is an antibody targeting PSMA. Anti-PSMA Antibody (1I379) can be used in ELISA,IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Anti-PSMA Antibody (1I379) is an antibody targeting PSMA. Anti-PSMA Antibody (1I379) can be used in ELISA,IHC. |
Synonyms | PSMAFGCP, PSMA, PSM, NAALADase I, NAALAdase, NAALAD1, mGCP, GIG27, GCPIImGCP, GCPII, GCP2, FOLHNAALADase I, FOLH1, FOLH, Folate hydrolase 1, FGCP |
Ig Type | Rabbit IgG |
Clone | 1I379 |
Reactivity | Human |
Verified Activity | IHC image of TMAH-00449 diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
Application | |
Recommended Dose | IHC:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type II membrane protein.; [Isoform PSMA']: Cytoplasm. |
Tissue Specificity | Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kid |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human PSMA |
Antigen Species | Human |
Gene Name | FOLH1 |
Gene ID | |
Uniprot ID | |
Biology Area | Cancer, Metabolism, Signal transduction |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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