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6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

🥰Excellent
Catalog No. T77685Cas No. 1207836-10-9

6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is a PDK1 inhibitor with anticancer and antiproliferative activity that can be used to study angiosarcoma, adenocarcinoma, multiple myeloma, psoriasis, prostate cancer, and Alzheimer's disease.

6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

🥰Excellent
Purity: 99.81%
Catalog No. T77685Cas No. 1207836-10-9
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is a PDK1 inhibitor with anticancer and antiproliferative activity that can be used to study angiosarcoma, adenocarcinoma, multiple myeloma, psoriasis, prostate cancer, and Alzheimer's disease.
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200 mg$29In Stock
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Purity:99.81%
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COA LCMS HNMR HPLC

Product Introduction

Bioactivity
Description
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is a PDK1 inhibitor with anticancer and antiproliferative activity that can be used to study angiosarcoma, adenocarcinoma, multiple myeloma, psoriasis, prostate cancer, and Alzheimer's disease.
Chemical Properties
Molecular Weight252.07
FormulaC9H6BrN3O
Cas No.1207836-10-9
SmilesCOc1cc(Br)cn2ncc(C#N)c12
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 5.63 mg/mL (22.32 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9672 mL19.8358 mL39.6715 mL198.3576 mL
5 mM0.7934 mL3.9672 mL7.9343 mL39.6715 mL
10 mM0.3967 mL1.9836 mL3.9672 mL19.8358 mL
20 mM0.1984 mL0.9918 mL1.9836 mL9.9179 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

PDK1
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