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N4Py
(Synonyms: N-4-Py, N 4 Py) Copy Product Info
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Synonyms: N-4-Py, N 4 Py
Catalog No. T25844 Copy Product Info
Purity: 99.25%
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N4Py is a pentadentate ligand capable of forming stable coordination complexes with metal ions such as iron and copper. It can mimic the metal-binding domain of Bleomycin. The Fe(II)-N4Py complex catalyzes the generation of reactive oxygen species (ROS), leading to oxidative DNA damage and strand breaks. Due to its ability to induce oxidative stress and DNA damage, the N4Py system is widely used in studies of anticancer mechanisms.
Cas No. 167695-87-6
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $80 | - | In Stock | |
| 5 mg | $189 | - | In Stock | |
| 10 mg | $279 | - | In Stock | |
| 25 mg | $469 | - | In Stock | |
| 50 mg | $688 | - | In Stock | |
| 100 mg | $979 | - | In Stock | |
| 500 mg | $1,960 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.25%
Appearance:Oil
Color:Yellow
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | N4Py is a pentadentate ligand capable of forming stable coordination complexes with metal ions such as iron and copper. It can mimic the metal-binding domain of Bleomycin. The Fe(II)-N4Py complex catalyzes the generation of reactive oxygen species (ROS), leading to oxidative DNA damage and strand breaks. Due to its ability to induce oxidative stress and DNA damage, the N4Py system is widely used in studies of anticancer mechanisms. |
| Synonyms | N-4-Py, N 4 Py |
| Molecular Weight | 367.45 |
| Formula | C23H21N5 |
| Cas No. | 167695-87-6 |
| Smiles | N=1C=CC=CC1CN(CC2=NC=CC=C2)C(C3=NC=CC=C3)C4=NC=CC=C4 |
| Relative Density. | 1.208 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Related Tags: N4Py chemical structure | N4Py formula | N4Py molecular weight
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