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Anti-C1 inhibitor Antibody (4P478)
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Catalog No. TMAY-01437
Alias serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Anti-C1 inhibitor Antibody (4P478) is a Mouse antibody targeting C1 inhibitor. Anti-C1 inhibitor Antibody (4P478) can be used in ELISA(Cap).
Anti-C1 inhibitor Antibody (4P478)
Anti-C1 inhibitor Antibody (4P478)
😃Good
Catalog No. TMAY-01437Alias serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Anti-C1 inhibitor Antibody (4P478) is a Mouse antibody targeting C1 inhibitor. Anti-C1 inhibitor Antibody (4P478) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA(Cap) Reactivity: Human |
| Alias | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| Ig Type | Mouse IgG2b |
| Clone | 4P478 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human C1 inhibitor / SerpinG1 (rh C1 inhibitor / SerpinG1; TMPY-01183; NP_000053.2; Met1-Ala500). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides and E-selectin. Owing to this moiety, C1-INH intervenes in regulation of the inflammatory reaction. The heterozygous deficiency of C1-INH results in hereditary angioedema (HAE). Owing to its ability to modulate the contact and complement systems and the convincing safety profile, plasma-derived C1 inhibitor is an attractive therapeutic protein to treat inflammatory diseases other than HAE. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human C1 inhibitor / SerpinG1 Protein (TMPY-01183) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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