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Anti-LRP1 Antibody (1R508)

(Synonyms: TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR) Copy Product Info
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Synonyms: TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR

Catalog No. TMAH-00704 Copy Product Info
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Anti-LRP1 Antibody (1R508) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (1R508) can be used in ELISA,IHC,WB.
Anti-LRP1 Antibody
(1R508)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LRP1 Antibody (1R508) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (1R508) can be used in ELISA,IHC,WB.
SynonymsTGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR
Ig Type
Rabbit IgG
Clone
1R508
Reactivity
Human, Mouse, Rat
Application
Recommended Dose
WB:1:500-1:2000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular Localization[Low-density lipoprotein receptor-related protein 1 85 kDa subunit]: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 515 kDa subunit]: Cell membrane; Peripheral membrane protein; Extracellular side. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 intracellular domain]: Cytoplasm. Nucleus.; Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center.
Tissue SpecificityMost abundant in liver, brain and lung.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundEndocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor. Acts as TAU/MAPT receptor and controls the endocytosis of TAU/MAPT as well as its subsequent spread. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. (Microbial infection) Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human LRP1
Antigen Species
Human
Gene Name
LRP1
Gene ID
Uniprot ID
Biology Area
Neuroscience, Cancer, Cardiovascular, Cell biology, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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