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Synonyms: TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-LRP1 Antibody (1R508) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (1R508) can be used in ELISA,IHC,WB. |
| Synonyms | TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR |
| Ig Type | Rabbit IgG |
| Clone | 1R508 |
| Reactivity | Human, Mouse, Rat |
| Application | |
| Recommended Dose | WB:1:500-1:2000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | [Low-density lipoprotein receptor-related protein 1 85 kDa subunit]: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 515 kDa subunit]: Cell membrane; Peripheral membrane protein; Extracellular side. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 intracellular domain]: Cytoplasm. Nucleus.; Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center. |
| Tissue Specificity | Most abundant in liver, brain and lung. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor. Acts as TAU/MAPT receptor and controls the endocytosis of TAU/MAPT as well as its subsequent spread. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. (Microbial infection) Functions as a receptor for Pseudomonas aeruginosa exotoxin A. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human LRP1 |
| Antigen Species | Human |
| Gene Name | LRP1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience, Cancer, Cardiovascular, Cell biology, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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