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Anti-PSGL-1/CD162 Polyclonal Antibody

(Synonyms: selectin P ligand, PSGL-1, PSGL1, CLA, CD162) Copy Product Info
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Synonyms: selectin P ligand, PSGL-1, PSGL1, CLA, CD162

Catalog No. TMAB-01588 Copy Product Info
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Anti-PSGL-1/CD162 Polyclonal Antibody is a Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Polyclonal Antibody can be used in WB.
Anti-PSGL-1/CD162 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PSGL-1/CD162 Polyclonal Antibody is a Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Polyclonal Antibody can be used in WB.
Synonymsselectin P ligand, PSGL-1, PSGL1, CLA, CD162
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityExpressed on neutrophils, monocytes and most lymphocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PSGL-1/CD162
Antigen Species
Human
Gene Name
SELPLG
Gene ID
Protein Name
P-selectin glycoprotein ligand 1
Uniprot ID
Biology Area
Cell adhesion molecules,Adhesion
Function
A SLe(x)-type glycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. PSGL1 is critical for the initial leukocyte capture.
Chemical Properties
Molecular WeightTheoretical: 41 kDa. Actual: 41 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-PSGL-1/CD162 Polyclonal Antibody molecular weight