I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 μg | In stock | $ 106.00 | |
100 μg | 5 days | $ 296.00 | |
200 μg | 5 days | $ 527.00 | |
500 μg | 5 days | $ 1,750.00 |
Biological Information | Testing in progress |
Description | I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family. |
Species | Human |
Expression System | E. coli |
Tag | Tag Free |
Accession Number | O14625 |
Synonyms | SCYB9B, I-TAC, chemokine (C-X-C motif) ligand 11, H174, SCYB11, IP9, b-R1, IP-9 |
Construction | A DNA sequence encoding the mature form of human CXCL11 (O14625) (Phe22-Phe94) was expressed with an initial Met. |
Protein Purity |
> 95 % as determined by SDS-PAGE
|
Molecular Weight | Approxiamtely 8.3 kDa |
Endotoxin | Please contact us for more information. |
Formulation | Lyophilized from sterile 40% acetonitrile, 1% TFAPlease contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Reconstitution | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CXCL11 Protein, Human, Recombinant SCYB-11 SCYB9B I-TAC H-174 SCYB 11 chemokine (C-X-C motif) ligand 11 H174 H 174 IP 9 SCYB11 IP9 b-R1 IP-9 recombinant recombinant-proteins proteins protein