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ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
(Synonyms: suppression of tumorigenicity 2, ST2V, ST2L, Protein T1, Protein ST2, Lymphocyte antigen 84, Ly84, Interleukin-1 receptor-like 1, IL-33R, IL-1RL1, Il1rl1, IL-1 R4, Fit-1, DER4) Copy Product InfoSynonyms: suppression of tumorigenicity 2, ST2V, ST2L, Protein T1, Protein ST2, Lymphocyte antigen 84, Ly84, Interleukin-1 receptor-like 1, IL-33R, IL-1RL1, Il1rl1, IL-1 R4, Fit-1, DER4
Catalog No. TMPJ-00850 Copy Product Info
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $48 | 7-10 days | 7-10 days | |
| 10 µg | $75 | - | In Stock | |
| 20 µg | $112 | 7-10 days | 7-10 days | |
| 50 µg | $197 | 7-10 days | 7-10 days | |
| 100 µg | $338 | 7-10 days | 7-10 days | |
| 200 µg | $586 | 7-10 days | 7-10 days | |
| 500 µg | $1,220 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>99.99%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Mouse ST2-His at 5μg/ml (100 μl/well) can bind Rhesus Macaque IL-33-His. The ED50 of Rhesus Macaque IL-33-His is 82.03 ng/ml. (Regularly tested) |
| Description | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | P14719-2 |
| Amino Acid | Ser27-Ala337 |
| Construction | Ser27-Ala337 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified)  |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | suppression of tumorigenicity 2, ST2V, ST2L, Protein T1, Protein ST2, Lymphocyte antigen 84, Ly84, Interleukin-1 receptor-like 1, IL-33R, IL-1RL1, Il1rl1, IL-1 R4, Fit-1, DER4 |
| Research Background | ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity. |
| Molecular Weight | 55-70 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) chemical structure | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) molecular weight
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