PBCRBS Traditional Chinese Medicine Compound Library

Catalog No. L6750

Library Compound List Excel SDF

The concept of “Promoting Blood Circulation for Removing Blood Stasis” (PBCRBS) is an important theory and therapeutic principle in traditional Chinese medicine (TCM). Common traditional Chinese medicines for PBCRBS include Ligusticum chuanxiong, Persica, Boswellia, and Myrrha, etc. These herbs are often characterized by pungent (xin), bitter (ku), and warm (wen) properties, allowing them to invigorate blood circulation and dispel stasis, exhibiting PBCRBS. Modern pharmacological research has shown that traditional Chinese medicines for PBCRBS have effects of improving hemodynamic abnormalities, hemorheological abnormalities, microcirculation disorders; resisting thrombosis, atherosclerosis, myocardial ischemia; inhibiting tissue abnormal proliferation, tumor growth; and shows analgesic effects. They are widely used in the treatment of cardiovascular and cerebrovascular diseases, diabetes, cirrhosis, and other conditions, demonstrating significant clinical efficacy and showing promising application.

Traditional Chinese medicines have multiple components and targets. The active components of a single TCM are diverse and each has different functions. An active component can influence multiple pathways. For example, curcumin, an active component of turmeric, can treat atrial fibrillation (AF) in rats by affecting the interleukin-17 (IL-17) signaling pathway. It can also exert neuroprotective effects in rats by activating the cyclic AMP response element-binding protein (CREB)/brain-derived neurotrophic factor (BDNF) signaling pathway.

To study the main active components and their mechanisms of action in PBCRBS TCMs, TargetMol has curated a library called “PBCRBS Traditional Chinese Medicine Compound Library” which consists of 588 compounds.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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Product discription

A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.
Compounds sourced from over 40 TCMs with blood circulation-promoting and blood stasis-removing effects, including safflower, turmeric, Garden Balsam Seed, myrrh, etc.
With diverse structures, encompassing terpenes, alkaloids, flavonoids, and other structurally diverse compounds.
Detailed compound information on structures, targets, IC50 and activity descriptions.
NMR and HPLC/LCMS validated to ensure high purity and quality.
Comprehensive instructions on product handling, solvent selection, storage methods and concentration choice for initial screening.

Library Customization

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Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

10. Blood. 2021, 137(11): 1478-1490. 11. Nucleic Acids Research. 2021. 12. Nature Communications. 2023, 14(1): 7574. 13. Advanced Science. 2020, 7(16): 2000925. 14. Angewandte Chemie. 2021. 15. Acta Pharmaceutica Sinica B. 2022. 16. Protein & Cell. 2021, 12(11): 877-888. 17. Bone Research. 2023, 11(1): 54. 18. Pharmacology & Therapeutics. (2021): 107930. 19. Nature Communications. 2021, 12(1): 1-12. 20. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Endogenous Metabolite (138)

Apoptosis (87)

Autophagy (56)

Antibacterial (49)

Reactive Oxygen Species (31)

NF-κB (28)

Antioxidant (28)

Antifungal (27)

COX (26)

P450 (20)

Influenza Virus (18)

HIV Protease (15)

GABA Receptor (13)

Parasite (13)

AChE (12)

DNA/RNA Synthesis (11)

Nrf2 (10)

Estrogen Receptor/ERR (10)

NO Synthase (9)

Virus Protease (9)

Anti-infection (9)

IL Receptor (9)

ROS (9)

Caspase (9)

MMP (8)

HSV (8)

TNF (7)

Lipoxygenase (7)

AChR (7)

Estrogen/progestogen Receptor (7)

Antibiotic (7)

HIF/HIF Prolyl-Hydroxylase (7)

AMPK (7)

TRP/TRPV Channel (7)

Beta Amyloid (7)

PPAR (7)

Mitophagy (7)

Akt (7)

5-HT Receptor (6)

EGFR (6)

JNK (6)

Dehydrogenase (6)

PKC (5)

ERK (5)

MAO (5)

Mitochondrial Metabolism (5)

NOS (5)

Tyrosinase (5)

PI3K (5)

PARP (5)

STAT (5)

Dopamine Receptor (4)

P-gp (4)

Ferroptosis (4)

Potassium Channel (4)

PDE (4)

Prostaglandin Receptor (4)

Androgen Receptor (4)

Sirtuin (4)

Calcium Channel (4)

p38 MAPK (4)

HBV (4)

Wnt/beta-catenin (4)

Reductase (4)

Adrenergic Receptor (3)

IκB/IKK (3)

SARS-CoV (3)

Immunology/Inflammation related (3)

HSP (3)

CDK (3)

VEGFR (3)

FGFR (3)

Glucosidase (3)

Antifection (3)

p53 (3)

BCL (3)

Phospholipase (3)

mTOR (2)

Epigenetic Reader Domain (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Monoamine Oxidase (2)

Casein Kinase (2)

GSK-3 (2)

Phosphatase (2)

PKA (2)

Histamine Receptor (2)

HER (2)

Antiviral (2)

TLR (2)

GST (2)

iGluR (2)

Reverse Transcriptase (2)

JAK (2)

Topoisomerase (2)

Aminopeptidase (2)

ATPase (2)

S6 Kinase (2)

Glucocorticoid Receptor (2)

HMG-CoA Reductase (2)

Src (2)

FAAH (2)

Syk (2)

HDAC (2)

Transferase (2)

Imidazoline Receptor (1)

Transaminase (1)

Carbonic Anhydrase (1)

NADPH-oxidase (1)

MEK (1)

FAK (1)

Sodium Channel (1)

Histone Acetyltransferase (1)

NOD (1)

PKM (1)

Cannabinoid Receptor (1)

PAI-1 (1)

NADPH (1)

Trk receptor (1)

Serine/threonin kinase (1)

Bcr-Abl (1)

DNA Alkylator/Crosslinker (1)

Glucokinase (1)

Leukotriene Receptor (1)

FXR (1)

Nucleoside Antimetabolite/Analog (1)

Liver X Receptor (1)

Cysteine Protease (1)

Serine Protease (1)

Drug Metabolite (1)

Antifolate (1)

Adenosine Receptor (1)

Melatonin Receptor (1)

aconitase (1)

Progesterone Receptor (1)

Glutathione Peroxidase (1)

RAAS (1)

PERK (1)

Gamma-secretase (1)

Phosphorylase (1)

Monocarboxylate transporter (1)

CYP19A1 (1)

HCV Protease (1)

TGF-beta/Smad (1)

DHFR (1)

CaMK (1)

GluR (1)

Lipase (1)

Epoxide Hydrolase (1)

Xanthine Oxidase (1)

PTEN (1)

ROR (1)

CXCR (1)

Integrin (1)

Stearoyl-CoA Desaturase (SCD) (1)

Hedgehog/Smoothened (1)

PDGFR (1)

Fatty Acid Synthase (1)

Chloride channel (1)

Opioid Receptor (1)

Aurora Kinase (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty