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Phenoxyethanol

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Catalog No. T20293Cas No. 122-99-6
Alias NSC-1864, NSC1864, NSC 1864

Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.

Phenoxyethanol

Phenoxyethanol

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Purity: 99.47%
Catalog No. T20293Alias NSC-1864, NSC1864, NSC 1864Cas No. 122-99-6
Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$48In StockIn Stock
1 mL x 10 mM (in DMSO)$45-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.47%
Appearance:Liquid
Color:Transparent
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Product Introduction

Phenoxyethanol AI Summary
Phenoxyethanol exhibits a diverse range of bioactivities. It acts as an inhibitor of RecQ-Like DNA Helicase 1 and Aldehyde Dehydrogenase 1 with potencies of 12589.3 nM and 39810.7 nM, respectively. Additionally, it functions as an agonist for retinoid X receptor alpha, androgen receptor, and thyroid hormone receptor beta signaling, showing potencies from 15848.9 nM to 4.0 nM. It also antagonizes androgen receptor and glucocorticoid receptor signaling with potencies of 1000000.0 nM and 0.7 nM respectively. The compound affects cell viability in LYMP2-005 and S16 Schwann cell assays with potencies of 3162.3 nM and 80.9 nM. It activates several pathways, including p53, rat pregnane X receptor, and the fibrous dysplasia/McCune-Albright syndrome pathway, with potencies from 56234.1 nM to 8912.5 nM, and inhibits Polymerase Iota at 79432.8 nM. In antiviral assays, it blocks Ebola Virus entry with AC50 values ranging from 562.3 nM to 7.943 µM. Furthermore, Phenoxyethanol shows antibacterial activity against Staphylococcus aureus MN8, more effectively reducing bacterial activity and inhibiting toxin TSST-1 production at a 0.10% concentration compared to 0.50% after 24 hours..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.
SynonymsNSC-1864, NSC1864, NSC 1864
Chemical Properties
Molecular Weight138.16
FormulaC8H10O2
Cas No.122-99-6
SmilesOCCOC=1C=CC=CC1
Relative Density.1.11. Temperature:20 °C.
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (398.09 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (14.48 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.2380 mL36.1899 mL72.3798 mL361.8992 mL
5 mM1.4476 mL7.2380 mL14.4760 mL72.3798 mL
10 mM0.7238 mL3.6190 mL7.2380 mL36.1899 mL
20 mM0.3619 mL1.8095 mL3.6190 mL18.0950 mL
50 mM0.1448 mL0.7238 mL1.4476 mL7.2380 mL
100 mM0.0724 mL0.3619 mL0.7238 mL3.6190 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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