Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Iliparcil

🥰Excellent
Catalog No. T67991Cas No. 137214-72-3

Iliparcil is an antithrombotic compound with oral activity.

Iliparcil

Iliparcil

🥰Excellent
Purity: 100%
Catalog No. T67991Cas No. 137214-72-3
Iliparcil is an antithrombotic compound with oral activity.
Pack SizePriceAvailabilityQuantity
1 mg$126In Stock
5 mg$323In Stock
10 mg$467In Stock
25 mg$708In Stock
50 mg$987In Stock
100 mg$1,350In Stock
200 mg$1,830In Stock
Add to Cart
Add to Quotation
Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
Questions
View More

Batch Information

Select Batch
Purity:100%
Contact us for more batch information

Resource Download

Product Introduction

Bioactivity
Description
Iliparcil is an antithrombotic compound with oral activity.
In vivo
The effect of Iliparcil, a new orally active beta-D-xyloside venous antithrombotic, was studied on the thrombosis following thrombolytic therapy in rats, using a modified Umetsu model. The compound was administered by oral route prior to thrombolytic therapy, which consisted of administering a combination of heparin and urokinase (H/U) at 37.5 and 70,000 IU/kg, respectively. Time to occlusion increased from 3.9 min with saline to 10.5 min following H/U injection. When Iliparcil (30 mg/kg, oral route) was administered 4 h before H/U injection, the time to occlusion was increased by 250% compared with H/U alone (p < 0.001). Similarly, dermatan sulfate (DS), administered intravenously (3 mg/kg) 5 min before thrombus induction, also increased the time to occlusion (300% compared with H/U alone; p < 0.001). It was also shown that times to occlusion following Iliparcil or DS treatments were still increased even when heparin dosage was decreased.[1]
Chemical Properties
Molecular Weight338.38
FormulaC16H18O6S
Cas No.137214-72-3
SmilesC(C)C=1C=2C(=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)CS3)=CC2)OC(=O)C1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (147.76 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9553 mL14.7763 mL29.5526 mL147.7629 mL
5 mM0.5911 mL2.9553 mL5.9105 mL29.5526 mL
10 mM0.2955 mL1.4776 mL2.9553 mL14.7763 mL
20 mM0.1478 mL0.7388 mL1.4776 mL7.3881 mL
50 mM0.0591 mL0.2955 mL0.5911 mL2.9553 mL
100 mM0.0296 mL0.1478 mL0.2955 mL1.4776 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Iliparcil | purchase Iliparcil | Iliparcil cost | order Iliparcil | Iliparcil chemical structure | Iliparcil in vivo | Iliparcil formula | Iliparcil molecular weight