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Licorice-saponin H2

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Catalog No. TN2289Cas No. 118441-85-3
Alias Licoricesaponin H2

Licorice-saponin H2 (Licoricesaponin H2) is a natural product

Licorice-saponin H2
Other Forms of Licorice-saponin H2:
Licorice-saponin H2 ammoniumTN80852484765-33-3
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Licorice-saponin H2

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🥰Excellent
Purity: 99.76%
Catalog No. TN2289Alias Licoricesaponin H2Cas No. 118441-85-3
Licorice-saponin H2 (Licoricesaponin H2) is a natural product
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$105In StockIn Stock
5 mg$259In StockIn Stock
10 mg$413In StockIn Stock
25 mg$673In StockIn Stock
1 mL x 10 mM (in DMSO)$237In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.76%
Color:White
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Licorice-saponin H2 (Licoricesaponin H2) is a natural product
In vitro
Eight purified components from Glycyrrhiza, namely glabridin, glycyrrhetinic acid, glycyrrhizin, licochalcone A, Licoricesaponin H2 , licoricesaponin G2, liquiritigenin and liquiritin were evaluated for their antimutagenicity against MNU in the Ames assay with S. typhimurium TA1535. Glycyrrhetinic acid, glycyrrhizin, licoricesaponin G2, Licoricesaponin H2 and liquiritin did not show the antimutagenicity against MNU in S. typhimurium TA1535. Glabridin, licochalcone A and liquiritigenin reduced revertant colonies derived from MNU in S. typhimurium TA1535 without showing cytotoxic effects, indicating that these compounds possess antimutagenic activity against MNU. The inhibitory activity of glabridin and licochalcone A was more effective than that of liquiritigenin.
SynonymsLicoricesaponin H2
Chemical Properties
Molecular Weight822.93
FormulaC42H62O16
Cas No.118441-85-3
Smiles[H][C@@]1(O[C@@H]2[C@@H](O)[C@H](O)[C@H](O[C@@]2([H])O[C@H]2CC[C@@]3(C)[C@@]([H])(CC[C@]4(C)[C@]3([H])C(=O)C=C3[C@]5([H])C[C@@](C)(CC[C@]5(C)CC[C@@]43C)C(O)=O)C2(C)C)C(O)=O)O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
Relative Density.1.43 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2152 mL6.0759 mL12.1517 mL60.7585 mL
5 mM0.2430 mL1.2152 mL2.4303 mL12.1517 mL
10 mM0.1215 mL0.6076 mL1.2152 mL6.0759 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

triterpeneoligoglycosideLicorice-saponin H-2Licorice-saponin H2Licorice saponin H2Inhibitorinhibit(18β,20α)-Glycyrrhizic acid
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