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Anti-Phospho-BLK (Tyr501) Polyclonal Antibody (Synonyms: p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-T...)

Catalog No. TMAC-00446 Copy Product Info
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Anti-Phospho-BLK (Tyr501) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLK (Tyr501). Anti-Phospho-BLK (Tyr501) Polyclonal Antibody can be used in IHC.

Anti-Phospho-BLK (Tyr501) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00446
Synonyms p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501)

Anti-Phospho-BLK (Tyr501) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLK (Tyr501). Anti-Phospho-BLK (Tyr501) Polyclonal Antibody can be used in IHC.

Anti-Phospho-BLK
(Tyr501) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2167-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-BLK (Tyr501) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLK (Tyr501). Anti-Phospho-BLK (Tyr501) Polyclonal Antibody can be used in IHC.
Synonymsp-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501)
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BLK (Phospho-Tyr501) antibody TMAC-00446 (left)or the same antibody preincubated with blocking peptide (right).
verifiedActivity
Application
Recommended Dose
IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundNon-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 57 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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