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Anti-Phospho-BLK (Tyr501) Polyclonal Antibody
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Catalog No. TMAC-00446
Alias p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501)
Anti-Phospho-BLK (Tyr501) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLK (Tyr501). Anti-Phospho-BLK (Tyr501) Polyclonal Antibody can be used in IHC.
Anti-Phospho-BLK (Tyr501) Polyclonal Antibody
Anti-Phospho-BLK (Tyr501) Polyclonal Antibody
😃Good
Catalog No. TMAC-00446Alias p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501)
Anti-Phospho-BLK (Tyr501) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLK (Tyr501). Anti-Phospho-BLK (Tyr501) Polyclonal Antibody can be used in IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-BLK (Tyr501) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLK (Tyr501). Anti-Phospho-BLK (Tyr501) Polyclonal Antibody can be used in IHC. |
| Synonyms | p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BLK (Phospho-Tyr501) antibody TMAC-00446 (left)or the same antibody preincubated with blocking peptide (right).  |
| Application | |
| Recommended Dose | IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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