IL-6R Protein, Human, Recombinant

Name: IL-6R Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPS-00089
Price: 119 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: IL-6RA, IL-6R1, CD126) Copy Product Info

Synonyms: IL-6RA, IL-6R1, CD126

Catalog No. TMPS-00089 Copy Product Info

IL-6R Protein, Human, Recombinant is expressed in CHO Cells. The accession number is P08887.

Pack Size	Price	USA Stock	Global Stock
5 µg	$119	-	In Stock
10 µg	$198	-	In Stock
20 µg	$368	7-10 days	7-10 days
50 µg	$849	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 0.2 μg/ml, measured in a cell proliferation assay using M1 cells in the presence of 10.0 ng/ml human IL-6.
Description	IL-6R Protein, Human, Recombinant is expressed in CHO Cells. The accession number is P08887.
Species	Human
Expression System	CHO Cells
Tag	Tag Free
Accession Number	P08887
Construction	Leu20-Phe365
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	IL-6RA, IL-6R1, CD126
Research Background	Interleukin-6 Receptor Alpha, also known as IL-6RA, IL-6R1 and CD126, belongs to the type I cytokine receptor family. It is mainly expressed on T cells, fibroblasts and macrophages. IL-6RA couples with gp130 to form the IL-6 receptor; IL-6RA binds specifically to IL-6 and depends on gp130 to transmit signals. IL-6RA dysfunction has been correlated with the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Soluble IL-6RA, which consists of only the extracellular domain of IL-6RA, acts as an agonist of IL-6 activity.

Chemical Properties

Molecular Weight

54~56 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.