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Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin that exhibits anti-inflammatory and antioxidative effects, offering protection against cardiac hypertrophy.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $83 | In Stock | |
| 5 mg | $197 | In Stock | |
| 10 mg | $289 | In Stock | |
| 25 mg | $489 | In Stock | |
| 50 mg | $713 | In Stock | |
| 100 mg | $987 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $238 | In Stock |
| Description | Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin that exhibits anti-inflammatory and antioxidative effects, offering protection against cardiac hypertrophy. |
| Targets&IC50 | Molt-3 cells:7.5 μM, CYP2C:1.4 μM, A549 cells:19.6 μM, U-937 cells:5.5 μM, HL-60 cells:7.5 μM, Caco-2 cells:82 μM, K562 cells:24 μM, HCC44 cells:20.3 μM |
| In vitro | Tamarixetin reduced the secretion of various inflammatory cytokines by dendritic cells after activation with LPS.?It also promoted the secretion of the anti-inflammatory cytokine interleukin (IL)-10 and specifically increased the population of IL-10-secreting immune cells in LPS-activated splenocytes.?Tamarixetin showed general anti-inflammatory effects in mouse models of bacterial sepsis and decreased bacteria abundance and endotoxin levels. |
| Synonyms | 4'-O-Methyl Quercetin |
| Molecular Weight | 316.26 |
| Formula | C16H12O7 |
| Cas No. | 603-61-2 |
| Smiles | COc1ccc(cc1O)-c1oc2cc(O)cc(O)c2c(=O)c1O |
| Relative Density. | 1.634 g/cm3 (Predicted) |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 4.4 mg/mL (13.91 mM), Sonication is recommended. | ||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.16 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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