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Anti-DLL4 Polyclonal Antibody (Alias: δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosop...)

Catalog No. TMAB-00554 Copy Product Info
🥰Excellent
Anti-DLL4 Polyclonal Antibody is a Rabbit antibody targeting DLL4. Anti-DLL4 Polyclonal Antibody can be used in WB.

Anti-DLL4 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-00554
Alias δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4

Anti-DLL4 Polyclonal Antibody is a Rabbit antibody targeting DLL4. Anti-DLL4 Polyclonal Antibody can be used in WB.

Anti-DLL4 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DLL4 Polyclonal Antibody is a Rabbit antibody targeting DLL4. Anti-DLL4 Polyclonal Antibody can be used in WB.
Synonymsδ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse)
Verified Activity
1. Sample:
Lane 1: Human K562 cell Lysates
Lane 2: Human THP-1 cell Lysates
Lane 3: Human 293T cell Lysates
Primary: Anti-DLL4 (TMAB-00554) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 75 kDa
Observed band size: 75 kDa
2. Tissue/cell: mouse embryo tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-Delta 4 Polyclonal Antibody, Unconjugated (TMAB-00554) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein (Probable).
Tissue SpecificityExpressed in vascular endothelium.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DLL4
Antigen Species
Human
Gene Name
DLL4
Gene ID
Protein Name
delta-like protein 4
Uniprot ID
Biology Area
Cell differentiation,Cell Differentiation,Notch Pathway
Function
Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.
Chemical Properties
Molecular WeightTheoretical: 72 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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