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Anti-Vinculin Polyclonal Antibody
(Synonyms: vinculin, MVCL, MV, HEL114, CMH15, CMD1W) Copy Product Info
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Synonyms: vinculin, MVCL, MV, HEL114, CMH15, CMD1W
Catalog No. TMAB-01967 Copy Product Info
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Anti-Vinculin Polyclonal Antibody is a Rabbit antibody targeting Vinculin. Anti-Vinculin Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P.
Anti-Vinculin Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Vinculin Polyclonal Antibody is a Rabbit antibody targeting Vinculin. Anti-Vinculin Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P. |
| Synonyms | vinculin, MVCL, MV, HEL114, CMH15, CMD1W |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 3ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| Tissue Specificity | Metavinculin is muscle-specific. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Vinculin |
| Antigen Species | Human |
| Gene Name | VCL |
| Gene ID | |
| Protein Name | Vinculin |
| Uniprot ID | |
| Biology Area | Cardiac arrhythmias,Actins,Actin Binding Proteins |
| Function | Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. |
| Molecular Weight | Theoretical: 125 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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