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SBDS Protein, Human, Recombinant (His)

Catalog No. TMPY-00518
Synonyms: CGI-97, Shwachman-Bodian-Diamond syndrome, SDS, SWDS

The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disorders, including hematopoietic dysfunction. SBDS deficiency leads to telomere shortening, that SBDS is a telomere-protecting protein that participates in regulating telomerase recruitment.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
SBDS Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
Description The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disorders, including hematopoietic dysfunction. SBDS deficiency leads to telomere shortening, that SBDS is a telomere-protecting protein that participates in regulating telomerase recruitment.
Species Human
Expression System E. coli
Tag His
Accession Number Q9Y3A5
Synonyms CGI-97, Shwachman-Bodian-Diamond syndrome, SDS, SWDS
Construction A DNA sequence encoding the human SBDS (Q9Y3A5) (Met1-Glu250) was expressed with a polyhistidine tag at the N-terminus.
Protein Purity > 95 % as determined by SDS-PAGE
Molecular Weight Approxiamtely 31 kDa
Endotoxin Please contact us for more information.
Formulation Lyophilized from sterile PBS, 10% glycerol. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disorders, including hematopoietic dysfunction. SBDS deficiency leads to telomere shortening, that SBDS is a telomere-protecting protein that participates in regulating telomerase recruitment.

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Keywords

SBDS Protein, Human, Recombinant (His) CGI-97 Shwachman-Bodian-Diamond syndrome CGI97 SDS SWDS CGI 97 recombinant recombinant-proteins proteins protein

 

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