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Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody (Synonyms: p-BLNK (Y84), p-BLNK (Tyr84), BLNK (p-Y84), BLNK (p-...)

Catalog No. TMAC-00448 Copy Product Info
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Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLNK (Tyr84). Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00448
Synonyms p-BLNK (Y84), p-BLNK (Tyr84), BLNK (p-Y84), BLNK (p-Tyr84)

Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLNK (Tyr84). Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-BLNK
(Tyr84) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3187-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLNK (Tyr84). Anti-Phospho-BLNK (Tyr84) Polyclonal Antibody can be used in IHC,WB.
Synonymsp-BLNK (Y84), p-BLNK (Tyr84), BLNK (p-Y84), BLNK (p-Tyr84)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from K562 cells, treated with starved (24hours), using BLNK (Phospho-Tyr84) antibody TMAC-00448. The lane on the right is treated with the synthesized peptide.
2. Immunohistochemistry analysis of paraffin-embedded human brain tissue using BLNK (Phospho-Tyr84) antibody TMAC-00448. The picture on the right is treated with the synthesized peptide.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-3000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundFunctions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 84 (E-M-Y(p)-V-M) derived from Human BLNK
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 65 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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