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EPZ032597

Name: EPZ032597
Brand: TargetMol
SKU: T70087
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T70087Cas No. 1887193-58-9

EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and can be used to prevent and treat pancreatic cancer.

EPZ032597

🥰Excellent

Purity: 99.70%

Catalog No. T70087Cas No. 1887193-58-9

EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and can be used to prevent and treat pancreatic cancer.

Pack Size	Price	Availability
1 mg	$350	In Stock
5 mg	$970	In Stock
10 mg	$1,200	In Stock
25 mg	$1,590	In Stock
50 mg	$1,980	In Stock
100 mg	$2,500	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.70%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and can be used to prevent and treat pancreatic cancer.

Chemical Properties

Molecular Weight	377.44
Formula	C₂₀H₂₃N₇O
Cas No.	1887193-58-9
Smiles	C(NC1CN(CC2=CN(CC3=CC=CC=C3)N=C2)C1)(=O)C4=CN(N=N4)C5CC5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (145.72 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6494 mL	13.2471 mL	26.4943 mL	132.4714 mL
5 mM	0.5299 mL	2.6494 mL	5.2989 mL	26.4943 mL
10 mM	0.2649 mL	1.3247 mL	2.6494 mL	13.2471 mL
20 mM	0.1325 mL	0.6624 mL	1.3247 mL	6.6236 mL
50 mM	0.0530 mL	0.2649 mL	0.5299 mL	2.6494 mL
100 mM	0.0265 mL	0.1325 mL	0.2649 mL	1.3247 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc